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Any questions about Inhibitor CHIR99021? See all about it in the post below. What is inhibitor CHIR99021? CHIR99021 (CT99021), is also known as 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile and CT99021. It is the most potent and selective inhibitor of GSK3. CHIR99021 is an aminopyrimidine derivative. It inhibits GSK3 β and GSK3 α. It also functions as a WNT activator. It … Continue reading Top 10 FAQs About Inhibitor CHIR99021
Meet Sam, our senior inbound marketing and social media coordinator at AG Scientific. He is a student at SDSU studying marketing. He shares a bit about himself in the post below. Q1. Could you introduce yourself? My name is Sam. I was born in Toronto, Canada, and I moved to San Diego I was 4 … Continue reading AG Scientific Spotlight: Sam Hashemian
The CHIR99021 GSK-3 Inhibitor is both potent and selective. Small membrane-permeable molecules are widely utilized for maintenance and differentiation of embryonic stem cells (ES) of different species. Glycogen synthase kinase 3 (GSK3) activates the Wnt/beta-catenin pathway when targeted for inhibition. GSK3 is a conserved signaling molecule with essential roles in diverse biological processes. GSK3 activity … Continue reading The CHIR99021 GSK-3 Inhibitor Mechanism
Before coming to AG Scientific, Inc., our intern Shannon spent a few months living in Washington DC. She shares a bit about herself in the post below. Q1. Could you introduce yourself? My name is Seungah, but you can call me Shannon. I am a participant of a Korea government program which is made for … Continue reading AG Scientific Spotlight: Shannon Park
Glioblastoma multiforme is the most aggressive and malignant form of gliomas, a group of tumors arising from glial cells of the brain. Glioblastomas are very difficult to treat due to the diffused nature of the tumor itself. The tumor cells have a distinct invasive feature of spreading and diffusing into different parts of the brain. … Continue reading Thapsigargin Applications: Glioblastoma Multiforme Studies
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Thapsia Garganica is a common Mediterranean weed, but highly toxic to sheep and cattle, thus earning the nickname “death carrot”. Thapsigargin is a natural cytotoxin derived from the plant Thapsia Graganica. Oncologists Samuel Denmeade at Johns Hopkins University, Baltimore and his team has extensively researched methods to harness thapsigargin’s toxicity, and develop, as result, a novel … Continue reading A Promising Cancer Therapy: Thapsigargin’s Anti-Cancer Roles
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Thapsigargin is a naturally occurring tumor promoter derived from the plant Thapsia garganica. This effect is a result of emptying the intracellular calcium stores, which leads to a chain of events that causes apoptosis. What is thapsigargin? Thapsigargin is a naturally occurring sesquiterpene lactone. Abundant research and literature have proved thapsigargin to be tumorigenic, capable of … Continue reading What is Thapsigargin: Thapsigargin FAQ
Innovative Discoveries: Science Presented at Neuroscience 2016 Neuroscience 2016 took place November 12-16 at the San Diego Convention Center. The Society for Neuroscience’s 46th annual meeting is the premier venue for neuroscientists to meet, present emerging science, learn from experts, collaborate with peers, explore new tools and technologies, and advance careers. There were more than … Continue reading Society of Neuroscience Holds Conference in San Diego
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Beta-lactam antibiotics contain a cyclic amide ring of which mimics the structure of the terminal amino acid residues comprising the peptidoglycan matrix. It is this structure that the enzyme beta lactamase acts upon as a method of antibiotic defense, hydrolyzing the ring and compromising the structure as a result. Structure and function are intrinsically related; … Continue reading Beta Lactamase Inhibitors in Research: Anti-Seizure
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Photograph: CEO Chip Lindgren and Dr. Linda M. Liau (His Neurosurgeon.) In June 2001, our CEO Chip Lindgren suddenly found out he was diagnosed with oligodendroglioma brain cancer. He was able to buy time with world leading surgeons that have over watched breakthroughs in cancer immunotherapy (immuno-oncology) and viral oncology research. Chip was one of the first … Continue reading Oncologic Neurosurgery: My Awake Brain Surgery