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21-Hydroxyoligomycin A

CAS: 102042-09-1 Formula: C45H74O12 MW: 807.1 Appearance: White Lyophilisate Purity: >95% by HPLC
Hazardous

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H-2481 1 mg
$321.98
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5 mg
$1,126.94
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*Please inquire the availability for this product. 21-Hydroxyoligomycin A is a rare member of the oligomycin class isolated as a co-metabolite of nemadectin, hence its original naming as nemadectin omega. 21-Hydroxyoligomycin A is structurally distinct and synthesized by a separate pathway from the nemadectins. Only limited literature references to this metabolite are available. However, in-house testing suggests that 21-hydroxyoligomycin has a more selective action against mammalian tumor cell lines than oligomycin A, exhibiting only weak antifungal and nematocidal activity.

 

Additional Information

Synonyms Nemadectin omega, LL-F28249 omega
Product # H-2481
CAS # 102042-09-1
Formula C45H74O12
MW 807.1
Appearance White Lyophilisate
Purity >95% by HPLC
Solubility Soluble in ethanol, methanol, DMF, and DMSO
Boiling Point 913.65° C at 760 mmHg (Predicted)
Storage Temp -20° C
Therapeutic Area Oncological Disorders
Use 21-hydroxyoligomycin has a more selective action against tumor cell.

Additional Information

MDL Number MFCD09752734
InChI InChI=1S/C45H74O12/c1-12-33-17-15-13-14-16-26(4)42(52)44(11,54)43(53)31(9)40(51)30(8)39(50)29(7)38(49)25(3)18-19-37(48)55-41-28(6)36(23-34(33)47)57-45(32(41)10)21-20-24(2)35(56-45)22-27(5)46/h13-15,17-19,24-36,38,40-42,46-47,49,51-52,54H,12,16,20-23H2,1-11H3/b14-13+,17-15+,19-18+/t24-,25-,26+,27+,28+,29-,30-,31-,32-,33-,34?,35-,36-,38+,40+,41+,42-,44-,45+/m1/s1
SMILES CC[C@@H]1/C=C/C=C/C[C@@H]([C@H]([C@@](C(=O)[C@@H]([C@H]([C@@H](C(=O)[C@@H]([C@H]([C@@H](/C=C/C(=O)O[C@H]2[C@H]([C@@H](CC1O)O[C@]3([C@@H]2C)CC[C@H]([C@H](O3)C[C@H](C)O)C)C)C)O)C)C)O)C)(C)O)O)C

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21-Hydroxyoligomycin A

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