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6BIO , GSK-3 Inhibitor

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6BIO , GSK-3 Inhibitor

CAS: 667463-62-9 Formula: C16H10BrN3O2 MW: 356.2 Appearance: Dark red Solid Purity: 98%
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B-1309 1 mg
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5 mg
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Inhibitor of phosphoinositide-dependentn kinase 1 (PDK1). Potent, reversible and ATP-competitive inhibitor of glycogen synthase kinase-3/ (GSK-3/) (IC= 5nM).

Additional Information

Synonyms [(2'z, 3'e)-6-Bromoindirubin-3'-oxime]
Product # B-1309
CAS # 667463-62-9
Chemical Name [(2'z, 3'e)-6-Bromoindirubin-3'-oxime]
Formula C16H10BrN3O2
MW 356.2
Appearance Dark red Solid
Purity 98%
Solubility Soluble in DMSO
Boiling Point 554.3±50.0 °C at 760 mmHg
Storage Temp -20°C
Therapeutic Area Oncological Disorders
Use A cell-permeable, potent, selective, reversible GSK-3α/β inhibitor in cancer

Additional Information

MDL Number MFCD08705318
ChemACX X1543894-7
InChI InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,18,22H,(H,19,21)/b15-13-,20-14+
SMILES c1ccc2c(c1)/C(=NO)/C(=C/3c4ccc(cc4NC3=O)Br)/N2

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GHS Pictograms
Handling Protect from moisture and Light

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6BIO , GSK-3 Inhibitor

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