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Calmodulin, Porcine
[C-1431]
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Product Name: Calmodulin, Porcine
Product# C-1431
Size & Price: 1 mg @ $60.00
Description: Calmodulin isolated from porcine brain is suitable for applications requiring active pure calmodulin.
Calmodulin (CaM) is a ubiquitous, calcium-binding protein that can bind to and regulate a multitude of different protein targets, thereby affecting many different cellular functions and calcium-calmodulin signal transduction pathways. CaM mediates processes such as inflammation, metabolism, apoptosis, muscle contraction, intracellular movement, short-term and long-term memory, nerve growth and the immune response
Molecular Weight: 16,750 Da
Active Product: Yes
Appearance: Lyophilized from 5% sucrose, 10 mM sodium phosphate, pH 7.0 at a protein concentration of approximately 1 mg per ml.
Purity: This preparation is greater than 98% by SDS-PAGE stained with Coomassie blue having a single band at approximately 17 kDa; Actual molecular weight is 16,750 Da.
Activity: Greater than 35,000 units per mg protein. One unit will stimulate 0.01 unit of 3':5'-cyclic nucleotide phosphodiesterase in a 3 ml reaction volume at pH 7.5 and 30C, to 50% of the maximum activity of the enzyme when saturated with CaM in the presence of 100 uM Ca2+.
Solubility: At a concentration of 1 mg per mL in Milli-Q water, CaM sample is a clear solution.
Handling: Store in Tightly Sealed Vial.
Storage: -20C.
Shipping: Express Courier
General Comments: The animal source of this product was collected at a USDA licensed establishment. The animals received ante and post mortem health inspection at the abattoir by a US FSIS inspector and they were apparently free from infectious and contagious diseases. All donor animals were sourced from the United States.
Reference: Massom, L., Lee, H., Jarrett, H.W. Trifluoperazine binding to porcine brain calmodulin and skeletal muscle troponin C. Biochemistry. 1990. 29:671.
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$60.00
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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