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Chelerythrine Chloride [C1021]
Description: Potent and selective inhibitor of Protein Kinase C.
Chemical Formula: C21H18ClNO4
Chemical Name: : 1,2-Dimethoxy-12-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
Molecular Weight: M.W. 383.8
Solubility: Soluble in Water and DMSO.
CAS Number: CAS [3895-92-9]
Boiling Point / Melting Point: BP/MP: 208-209°C
Active Product: N
Appearance: Yellow Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial.
Storage: -20°C.
Shipping: Express Courier
General Comments: For comprehensive literature review, please call (858) 452-9925.
Literature Reference: 1. Merck Index., 1996., 12:, 2093., 2. Eckly-Michel, A.E., A. Le Bec, C. Lugnier..
Literature Reference: Chelerythrine, a Protein Kinase C Inhibitor, Interacts with Cyclic Nucleotide Phosphodiesterases., European Journal of Pharmacology, 1997., 324(1):, 85-88., 3. Drata, J., J. Ulrichova, D. Walterova..
Literature Reference: Saguinarine and Chelerythrine as Inhibitors of Aromatic Amino Acid Decaroxylase., Journal of Enzyme Inhibition., 1996., 10(4):, 231-237., 4. Serrano, P.A., W.A. Rodriguez, B. Pope, E.L. Bennett, M.R. Rosenzweig..
Literature Reference: Protein Kinase C Inhibitor Chelerythrine Disrupts Memory Formation in Chicks., Behavioral Neuroscience., 1995., 109(2):, 278-284., 5. Herbert, J.M., J.M. Augereau, J. Gleye, J.P. Maffrand..
Literature Reference: Chelerythrine is a Potent and Specific Inhibitor of Protein Kinase C., Biochemical and Biophysical Research Communications, 1990., 172(3):, 993-999., 6. Ko, F.N., I.S. Chen, S.J. Wu, L.G. Lee, T.F. Haung, C.M. Teng..
Literature Reference: Antiplatlet Effects of Chelerythrine Chloride Isolated from Zanthoxylum simulans., Biochim. Biophys. Acta., 1990., 1052(3):, 360-365..
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