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Cyclopiazonic acid, Penicillium cyclopium
[C1025]
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Description: Reversible inhibitor of endoplasmic reticulum Ca2+ ATPase. Does not increase IP3 levels. Chemical Formula: C20H20N2O3 Molecular Weight: M.W. 336.4 Solubility: Soluble in Methylene Chloride and Methanol. CAS Number: CAS [18172-33-3] Boiling Point / Melting Point: BP/MP: 243-245°C Active Product: N Appearance: Off-White Crystals Purity: >97% Handling: Potent Neurotoxin. Wear gloves/mask when handling this product. Avoid contact by all modes of exposure. Storage: -20°C. Shipping: Express Courier Literature Reference: 1. Teshima, R., J. Onose, H. Ikebuchi, J. Sawada., Ca2+-ATPase Inhibitors and PKC Activation Synergistically Stimulate TNF-Alpha Production in RBL-2H3 Cells., 1998., 47(8):, 328-333., 2. Avellanal, M., P. Rodrieguez, S. Barrigon.. Literature Reference: Protective Effects of Cyclopiazonic Acid on Ischemia-Reperfusion Injury in Rabit Hearts., Journal of Cardiovasc. Pharmacol., 1998., 32(5):, 845-851., 3. Franck, H., M. Storr, A. Puschmann, V. Schusdziarra, H.D. Allescher.. Literature Reference: Involvement of Intracellular Ca2+ Stores in Inhibitory Effects of NO Donor SIN-1 and cGMP., Am. Journal Physiol., 1998., 275:, G159-G168.. Bulk Quantity: Inquire
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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