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CNQX
[C1053]
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Description: Potent kainate / quisqualate receptor antagonist.
Chemical Formula: C9H4N4O4
Chemical Name: : 6-cyano-7-nitroquinoxaline-2,3-dione
Molecular Weight: M.W. 232.16
Solubility: Soluble in DMSO or 0.1 N NaOH. Insoluble in Water.
CAS Number: CAS [115066-14-3]
Boiling Point / Melting Point: BP/MP: > 300°C
Active Product: N
Appearance: Light Yellow Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial. Protect from Light.
Storage: Room Temperature.
Shipping: Priority Courier
General Comments: Ask us about our Water Soluble Form of CNQX.
Literature Reference: 1. Honore, T., et al.., Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor Antagonists., 1998., 241:, 701., 2. Drejer, J., T. Honore..
Literature Reference: New Quinoxalinediones Show Potent Antagonism of Quisqualate Responses in Cultured Mouse Cortical Neurons., Neuroscience Letters., 1988., 87(1-2):, 104-108., 3. Turski, L., K. Bressler, T. Klockgether, D.N. Stephens.
Literature Reference: Differential Effects of the Excitatory Amino Acid Antagonist 6-Cyano-7-Nitroquinoxaline-2,3-dione (CNQX) and R(-)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP) on Spinal Reflex Activity in Mice., Neuroscience Letters., 1990., 113(1):, 66-71., 4. Pringle, A.K., F. Iannotti, G.J. Wilde, J.E. Chad, P.J. Seeley, L.E. Sundstrom.
Literature Reference: Neuroprotection by Both NMDA and Non-NMDA Receptor Antagonists in In Vitro Ischemia., Brain Research., 1997., 755(1):, 36-46., 5. Iwasaki, Y., K. Ikeda, T. Shiojima, M. Kinoshita..
Literature Reference: CNQX Prevents Spinal Motor Neuron Death Following Sciatic Nerve Transection in Newborn Rats., Journal of Neurological Sciences., 1995., 134(1-2):, 21-25., 6. Ball, E.F., P.J. Shaw, P.G. Ince, M. Johnson..
Literature Reference: The Distribution of Excitatory Amino Acid Receptors in the Normal Human Midbrain and Basal Ganglia with Implication for Parkinson's Disease: A Quantitative Autoradiographic Study using [3H]MK-801,[3H]Glycine, [3H]CNQX, [3H]Kainate., Brain Research., 1994., 658(1-2):, 209-218..
Bulk Quantity: Inquire
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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