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Concanamycin A, Streptomyces sp.
[C1057]
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Description: Antibiotic which is a specific inhibitor of vacuolar H+ ATPase.
Chemical Formula: C46H75NO14
Chemical Name: : Folimycin, Streptomyces sp.
Molecular Weight: M.W. 866.1
Solubility: Soluble in DSMO.
CAS Number: CAS [80890-47-7]
Active Product: N
Appearance: White Solid
Purity: >90%
Handling: Protect from Light.
Storage: -20°C.
Shipping: Express Courier
Literature Reference: 1. Kataoka, T., N. Shinohara, H. Takayama, K. Takaku, S. Kondo, S. Yonehara, K. Nagai., Concanamycin A, A Powerful Tool for Characterization and Estimation of Contribution of Perforin- and Fas-based Lyctic Pathways I Cell-Mediated Cytotoxicity., 1996., 156(10):, 3678-3686., 2. Akifusa, S., et al..
Literature Reference: Increase in Bcl-2 level Promoted by CD40 Ligation correlates with Inhibition of B Cell Apoptosis Induced by Vacuolar Type H (+)-ATPase Inhibitor., Exp. Cell. Res., 1998., 238(1):, 82-89., 3. Scott, D.A., R. Docampo..
Literature Reference: Two Types of H+-ATPase are Involved in the Acidifications of Internal Compartments in Trypanosoma Cruzi., Biochem. Journal., 1998., 331:, 583-589., 4. Guinea, R, L. Carrasco..
Literature Reference: Concanamycin A: A Powerful Inhibitor of Enveloped Animal-Virus Entry into Cells., Biochemical and Biophysical Research Communications., 1994., 201(3):, 1270-1278..
Bulk Quantity: Inquire
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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