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Cytochalasin D, Zygusporium mansonii [C1070]
Alternative Product ID: Zygosporin A.
Description: A fungal metabolite that acts as a potent inhibitor of actin filament and contractile microfilaments. Also shown to protect Hippocampal neurons from Amyloid beta-Peptide Toxicity.
Chemical Formula: C30H37NO6
Molecular Weight: M.W. 507.63
Solubility: Soluble in Ethanol.
CAS Number: CAS [22144-77-0].
Boiling Point / Melting Point: BP/MP 255-260 degrees celcius
Active Product: N
Appearance: White Solid
Purity: >97%
Handling: Protect from Light.
Storage: -20°C.
Shipping: Express Courier
Literature Reference: 1. Merck Index., 1996., 12:, 2859., 2. Abedi, H, I. Zachary..
Literature Reference: Cytochalasin D Stimulation of Tyrosine Phosphorylation and Phosphotyrosine-Associated Kinase Activity in Vascular Smooth Muscle Cells., Biochemical and Biophysical Research Communications., 1998., 245:, 646-650., 3. Elbling, L., W. Berger, R.M. Weiss, D. Printz, G. Fritsch, M. Micksche..
Literature Reference: A Novel Bioassay for P-glycoprotein Functionality using Cytochalasin D., Cytometry., 1998., 31(3):, 187-198., 4. Furukawa, K., M.P. Mattson..
Literature Reference: Cytochalasins protect Hippocampal Neurons against Amyloid Beta-Peptide Toxicity: Evidence that Actin Depolymerization suppresses Ca2+ Influx., J. Neurochem., 1995., 65(3):, 1061-1068..
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