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Diphenyleneiodonium chloride
[D1011]
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Description: Nitric Oxide inhibitor. Binds strongly to flavoproteins.
Chemical Formula: C12H8ICl
Molecular Weight: M.W. 314.55
Solubility: Soluble in DMSO.
CAS Number: CAS [4673-26-1]
Active Product: N
Appearance: White Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial.
Storage: -20°C.
Shipping: Express Courier
General Comments: For comprehensive literature review, please call (858) 452-9925.
Literature Reference: 1. Dodd-O, J.M., G. Zheng, H.S. Silverman, E.G. Lakatta, R.C. Ziegelstein., Endothelium-Independent Relaxation of Aortic Rings by the Nitric Oxide Synthase Inhibitor Diphenyleneiodonium., 1997., 120(5):, 857-864., 2. Wang, Y.X., C.I. Poon, C.C. Pang..
Literature Reference: Inhibitory Actions of Diphenyleneiodonium on Endothelium-Dependent Vasodilations., British Journal of Pharmacology., 1993., 110(3):, 1232-1238., 3. Rand, M.J., C.G. Li..
Literature Reference: The Inhibition of Nitric Oxide-Mediated Relaxations in the Rat Aorta and Anococcygeus Muscle by Diphenylene iodonium., Clinical and Experimental Pharmacology and Physiology., 1993., 20(3):, 141-148., 4. Hampton, M.B., C.C. Winterbourn..
Literature Reference: Modification of Neutrophil Oxidant Production with Diphenyleneiodonium and its Effects on Bacterial Killing., Free Radcial Biology and Medicine., 1995., 18(4):, 633-639., 5. McGuire, J.J., D.J. Anderson, B.M. Bennett..
Literature Reference: Inhibition of the Biotransformation and Pharmacological Actions of Glyceryl Trinitrate by the Flavoprotein Inhibitor, Diphenyleneiodonium., Journal of Pharmacology and Experimental Therapeutics., 1994., 271(2):, 708-714., 6. Wyatt, C.N., E.K. Weir, C. Peers..
Literature Reference: Diphenylene iodonium Blocks K+ and Ca2+ Currents in Type I Cells Isolated from the Neonatal Rat Carotid Body., Neuroscience Letters., 1994., 172(1-2):, 63-66..
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