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DETA-NONOate, NOC-18 [D1015]
Description: A Nitric Oxide donor, useful for reliable generation of Nitric Oxide (NO) in vitro or in vivo.
Chemical Formula: C4H13N5O2
Chemical Name: : (Z)-1-[2-(2-Aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate
Molecular Weight: M.W. 163.2
Solubility: Readily Soluble in Water.
CAS Number: CAS [146724-94-9]
Active Product: N
Appearance: White Crystalline Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial. Protect from Moisture.
Storage: -20°C.
Shipping: Express Courier
General Comments: For comprehensive literature review, please call (858) 452-9925.
Literature Reference: 1. Keefer, L.K., R.W. Nims, K.M. Davies, and D.A. Win, NONOates (1-Substitutes Diazen-1-ium-1,2-diolates) as Nitric Oxide Donors: Convenient Nitric Oxide Dosage Forms., 1996., 268:, 281-293., 2. Kong, L., G.D. Dunn, L.K. Keefer, R.J. Korthuis..
Literature Reference: Nitric Oxide reduces Tumor Cell Adhesion to Isolated Rat Postcapillary Venules., Clinical and Experimental Metastasis., 1996., 14(4):, 335-343., 3. Smith, D.J., et al..
Literature Reference: Nitric Oxide-Releasing Polymers Containing the [N(O)NO]- Group., Journal of Medicinal Chemistry., 1996., 39:, 1148-1156., 4. Mooradian, D.l., T.C. Hutsell, L.K. Keefer..
Literature Reference: Nitric Oxide (NO) Donor Molecules: Effects of NO Release Rate on Vascular Smooth Muscle Cell Proliferation In Vitro., Journal of Cardiovascular Pharmacology., 1995., 25(4):, 674-678., 5. Vanderford, P.A., J. Wong, R. Chang, L.K. Keefer, S.J. Soifer, J.R. Fineman..
Literature Reference: Diethylamine / Nitric Oxide (NO) Adduct, an NO Donor, produces Potent Pulmonary and Systemic Vasodilation in Intact Newborn Lambs., Journal of Cardiovascular Pharmacology., 1994., 23(1):, 113-119., 6. Inoue, T; Mashimo, T; Shibuta, S; Yoshiya, I..
Literature Reference: Intrathecal Administration of a New Nitric Oxide Donor, NOC-18, Produces Acute Thermal Hyperalgesia in the Rat., Journal of Neurological Sciences., 1997., 143(1):, 1-7..
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