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Epoxomicin, Synthetic
[E1098]
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Description: Cell permeable, potent, and selective proteasome inhibitor. More potent than Lactocystin. Inhibits the chymotrypsin-like, trypsin-like, and peptidylglutamyl peptide-hydrolyzing activities of the proteasome.
Chemical Formula: C28H50N4O7
Molecular Weight: M.W. 554.7
Solubility: Soluble in DMSO. Insoluble in Water.
Active Product: N
Appearance: White Solid
Purity: >95%
Handling: Store in Tightly Sealed Vial. Protect from Water.
Storage: -20°C.
Shipping: Express Courier
Literature Reference: 1. Meng, L. et al., Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity, 1999., 96:, 10403., 2. Sin, N. et al..
Literature Reference: Total synthesis of the potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology., Bioorg. Med. Chem. Lett., 1999., 9:, 2283., 3. Hanada, M., et al..
Literature Reference: Epoxomicin, a new antitumor agent of microbial origin., J. Antibiot., 1992., 45:, 1746..
Bulk Quantity: Inquire
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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