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FK-506 (FK506,Tacrolimus, Fujimycin) [F1030]
Alternative Product ID: Tacrolimus, Fujimycin
Description: FK506 is an immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein and inhibit the Ca2+-dependent phosphatase and calcineurin.
Chemical Formula: C44H69NO12
Molecular Weight: M.W. 804.0
Solubility: FK506 is soluble in DMSO, MeOH, also ETOAC. Suggested stock concentration in DMSO is 10mM. Also reported to provide clear colorless solution at >10mg/ml CH2CI2.
CAS Number: CAS [104987-11-3]
Active Product: Y
Appearance: Off-White Solid
Purity: >=99%
Handling: Store in Tightly Sealed Vial. Protect from light
Storage: -20 C recommended..
Shipping: Express Courier
Bulk Quantity: Inquire for 25mg & greater bulk quantity pricing.
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