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Geranylgeraniol
[G1013]
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Description: A potent inducer of apoptosis in numerous tumor cell lines. Also utilized for protein isoprenylation.
Chemical Formula: C20H34O
Chemical Name: : 3,7,11,15-Tetramethyl-2,6,10,14-hexadecatraen-1-ol
Molecular Weight: M.W. 290.5
CAS Number: CAS [24034-73-9]
Active Product: Call for availability / pricing information
Appearance: Clear Colorless Liquid
Purity: >95%
Handling: Store in Tightly Sealed Vial.
Storage: -20°C.
Shipping: Express Courier
General Comments: For comprehensive literature review, please call (858) 452-9925.
Literature Reference: 1. Masuda, Y., M. Nakaya, S. Nakajo, K. Nakaya., Geranylgeraniol Potently Induces Caspase-3-like Activity during Apoptosis in Human Leukemia U937 Cells., 1997., 234(3):, 641-645., 2. Poverino A.J., S.D. Patterson..
Literature Reference: Selective Activation of Caspases During Apototic Induction in HL-60 Cells. Effects of a Tetrapeptide Inhibitor., Journal of Biological Chemistry., 1997., 272(11):, 7013-7021., 3. McGuire, T.F., S.M. Sebti..
Literature Reference: Geranylgeraniol Potentiates Lovastatin Inhibition of Oncogenic H-Ras Processing and Signaling while Preventing Cytotoxicity., Oncogene., 1997., 14(3):, 305-312, 4. Miquel K., A. Pradines, G. Favre..
Literature Reference: Farnesol and Geranylgeraniol Induce Actin Cytoskeleton Disorganization and Apoptosis in A549 Lung Adenocarcinoma Cells., Biochemical and Biophysical Research Communications, 1996., 225(3):, 869-876., 5. Ohizumi, Y. Masuda, S. Nakajo, I. Sakai, S. Ohsawa, K. Nakaya..
Literature Reference: Geranylgeraniol is a Potent Inducer of Apoptosis in Tumor Cells., Journal Biochem (Tokyo)., 1995., 117(1):, 11-13., 6. Crick, DC; Andres, DA; Danesi, R; Macchia, M; Waechter, CJ..
Literature Reference: Geranylgeraniol Overcomes the Block of Cell Proliferation by Lovastatin in c6 Glioma Cells., Journal of Neurochemistry., 1998., 70(6):, 2397-2405..
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