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LY-333531.hydrochloride
[L1011]
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Description: Potent, selective inhibitor of Protein Kinase C isozymes, PKC beta I(IC50=4.7 nM) and PKC beta II (IC50=5.9 nM).
Chemical Formula: C28H28N403.HCl
Chemical Name: : (S)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-dione. hydrochloride
Molecular Weight: M.W. 468.6 . 36.5
Solubility: Soluble in DMSO
Active Product:
Appearance: Orange/Red Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial.
Storage: +4°C.
Shipping: Express Courier
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Literature Reference: 1. Jirousek, M. R., et al., (S)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-dione (LY333531) and Related analogues: Isozyme Selective Inhibitors of Protein Kinase C beta,, 1996., 39:, 2664-2671..
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