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clasto-Lactacystin beta-lactone, Synthetic[200 ug]
[L1055]
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Description: Highly specific, cell permeable, and irreversible 20S proteasome inhibitor. It is believed lactacystin acts as a precursor for clasto-lactacystin b-lactone..
Chemical Formula: C10H15NO4
Molecular Weight: M.W. 213.2
Solubility: Soluble in DMSO.
CAS Number: CAS [155975-72-7]
Active Product: N
Appearance: White Solid
Purity: >95%
Handling: Store in Tightly Sealed Vial.
Storage: -20°C.
Shipping: Express Courier
Literature Reference: 1. Fenteany, G. et al., Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin., 1995., 268:, 726., 2. Dick, L.R. et al..
Literature Reference: Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone., J. Biol. Chem., 1996., 271:, 7273., 3. Dick, L.R. et al..
Literature Reference: Mechanistic studies on the inactivation of the proteasome by lactacystin in cultured cells., et al.; J. Biol. Chem., 1997., 272:, 182., 4. Craiu, A..
Literature Reference: Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation., J. Biol. Chem., 1997., 272:, 13437..
Bulk Quantity: Inquire
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$275.00
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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