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MnTMPyP [M1020]
Description: Cell permeable SOD mimetic. Catalyzes the dismutation of O2- even in the presence of excess EDTA.
Chemical Formula: C44H42MnN8
Chemical Name: : Manganese (III) tetrakis(1-methyl-4-pyridyl)porphyrin
Molecular Weight: M.W. 737.8
Solubility: Soluble in Water.
Active Product: N
Appearance: Crystalline Solid
Purity: >95%
Handling: Store in Tightly Sealed Vial. Protect from Moisture.
Storage: +4°C.
Shipping: Express Courier
General Comments: For comprehensive literature review, please call (858) 452-9925.
Literature Reference: 1. Faulkner, K.M., S.I. Liochev, I. Fridovich., Stable Mn(III) Porphyrins Mimic Superoxide Dismutase In Vitro and Substitute for it In Vivo., 1994., 269(38):, 23471-23476., 2.Gardner, P.R., D.D. Nguyen, C.W. White..
Literature Reference: Superoxide Scavenging by Mn (II/III) tetrakis (1-methyl-4-pyridyl) porphyrin in Mammalian Cells., Archives of Biochemistry and Biophysics., 1996., 325(1):, 20-28., 3. Zingarelli, B., B.J. Day, J.D. Crapo, A.L. Salzman, C. Szabo..
Literature Reference: The Potential Role of Peroxynitrite in the Vascular Contractile and Cellular Energetic Failure in Endotoxic Shock., British Journal of Pharmacology., 1997., 120(2):, 259-267., 4. Szabo, C., B.J. Day, A.L. Salzman..
Literature Reference: Evaluation of the Relative Contribution of Nitric Oxide and Peroxynitrite to the Suppression of Mitochondrial Respiration in Immunostimulated Macrophages using a Manganese Mesoporphyrin Superoxide Dismutase Mimetic and Peroxynitrite Scavenger., FEBS Letters., 1996., 381(1-2):, 82-86., 5. Day, B.J., S. Shawen, S.I. Liochev, J.D. Crapo..
Literature Reference: A Metalloporphyrin Superoxide Dismutase Mimetic Protects Against Paraquat-Induced Lung Injury In Vivo., Journal of Pharmacology and ExperimentalTherapeutics., 1995., 275(3):, 1227-1232., 6. Day, B.J., J.D. Crapo..
Literature Reference: A Metalloporphyrin Superoxide Dismutase Mimetic Protects Against Paraquat-Induced Lung Injury In Vivo., Toxicology and Applied Pharmacology., 1996., 140(1):, 94-100..
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