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MAHMA-NONOate [M1030]
Description: A Nitric Oxide Donor, useful for the reliable generation of Nitric Oxide (NO) in vitro or in vivo. Half life (t1/2) for NO release at 37°C is 1-2 minutes.
Chemical Formula: C8H20N402
Chemical Name: : NOC-9, (Z)-1-[N-Methyl-N-[6-(N-methylammoniohexyl) amino]]diazen-1-ium-1,2-diolate
Molecular Weight: M.W. 204.3
Solubility: Soluble in Water.
CAS Number: CAS [146724-86-9]
Active Product: N
Appearance: White Crystalline Solid
Purity: >98%
Handling: Protect from Moisture. Prepare all solutions fresh daily.
Storage: -20°C.
Shipping: Express Courier
General Comments: For comprehensive literature review, please call (858) 452-9925.
Literature Reference: 1. Keefer, L.K., R.W. Nims, K.M. Davies, and D.A. Wi., NONOates (1-Substitutes Diazen-1-ium-1,2-diolates) as Nitric Oxide Donors: Convenient Nitric Oxide Dosage Forms., 1996., 298:, 281-293., 2. Smith, D.J., et al..
Literature Reference: Nitric Oxide-Releasing Polymers Containing the [N(O)NO]- Group., Journal of Medicinal Chemistry., 1996., 39:, 1148-1156., 3. Mooradian, D.l., T.C. Hutsell, L.K. Keefer..
Literature Reference: Nitric Oxide (NO) Donor Molecules: Effects of NO Release Rate on Vascular Smooth Muscle Cell Proliferation In Vitro., Journal of Cardiovascular Pharmacology., 1995., 25(4):, 674-678., Keefer, L.K., et al..
Literature Reference: In Nitrosamines and Related N-Nitroso Compounds: Chemistry and Biochemistry" (R.N. Loeppky and C.J. Michejda eds., American Chemical Society (ACS Symposium Series 553), Washington, D.C.., 1994., 136., 5. Maragos, C.M., J.M. Wang, J.A. Hrabie, J.J. Oppenheim, L.K. Keefer..
Literature Reference: Nitric Oxide / Nucleophile Complexes inhibit the In Vitro Proliferation of A375 Melanoma Cells via Nitric Oxide Release., Cancer Research., 1993., 53(3):, 564-568., 6. Morley, D., L.K. Keefer..
Literature Reference: Nitric Oxide / Nucleophile Complexes: A Unique Class of Nitric Oxide-Based Vasodilators., Journal of Cardiovascular Pharmacology., 1993., 22(Suppl. 7)., S3-S9..
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