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NBQX
[N1019]
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Description: NBQX is a potent and selective AMPA/Kainate receptor antagonist. NBQX is also neuroprotective agent.
Chemical Formula: C12H8N4O6S
Chemical Name: : 2,3-Dihydroxy-6-nitro-7-sulphamoylbenzo(f)-quinoxaline; 6-Nitro-7-sulphamoylbenzo(f)-quinoxaline-2,3-dionee
Molecular Weight: M.W. 336.28
Solubility: NBQX is Soluble in DMSO.
CAS Number: CAS [118876-58-7]
Active Product: Y
Appearance: Light Yellow Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial.
Storage: Room Temperature.
Shipping: Priority Courier
General Comments: For water soluble form of NBQX, refer to product # N-1020.
Literature Reference: 1. Honore, T., et al., Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor Antagonists., 1988., 241:, 701., 2.Lo, E.H., A.R. Pierce, J.B. Mandeville, B.R. Rosen..
Literature Reference: Neuroprotection with NBQX in Rat Focal Cerebral Ischemia. Effects on ADC Probability Distribution Functions and Diffusion-Perfusion Relationships., Stroke., 1997., 28(2):, 439-446., 3. Hu, P., N.H. Diemer, T. Bruhn, F.F. Johansen..
Literature Reference: Effects of the AMPA-Receptor Antagonist, NBQX, on Neuron Loss in Dentate Hilus of the Hippocampal Formation after 8, 10, or 12 Min of Cerebral Ischemia in the Rat., Journal of Cerebral Blood Flow and Metabolism., 1997., 17(2):, 147-152., 4. K. Overgaard, T. Sereghy, H. Pederson, G. Boysen..
Literature Reference: Neuroprotection with NBQX and Thrombolysis with RT-PA in Rat Embolic Stroke., Neurological Research., 1993., 15(5):, 344-349., 5. Lees, G.J., W. Leong..
Literature Reference: Differential Effects of NBQX on the Distal and Local Toxicity of Glutamate Agonists Administered Intra-Hippocampally., Brain Research., 1993., 628(1-2):, 1-7..
Bulk Quantity: Readily Available, Please Inquire
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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