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NBQX.2Na
[N1020]
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Description: New formulation. NBQX.2Na is water soluble form of NBQX (N1019). This product is a potent and selective AMPA/Kainate receptor antagonist. Neuroprotective and anticonvulsive invivo.
Chemical Formula: C12H6N4O6S.2Na
Chemical Name: 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt.
Molecular Weight: M.W. 380.24
Solubility: Soluble in water (soluble to 100mM)
Active Product: Y
Appearance: Red to Brown Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial. Protect from light.
Storage: +4C.
Shipping: Priority Courier
General Comments: Refer to product N1019 for non-water soluble form.
Literature Reference: 1. Honore, T., et al., Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor Antagonists., 1988., 241:, 701., 2.Lo, E.H., A.R. Pierce, J.B. Mandeville, B.R. Rosen..
Literature Reference: Neuroprotection with NBQX in Rat Focal Cerebral Ischemia. Effects on ADC Probability Distribution Functions and Diffusion-Perfusion Relationships., Stroke., 1997., 28(2):, 439-446., 3. Hu, P., N.H. Diemer, T. Bruhn, F.F. Johansen..
Literature Reference: Effects of the AMPA-Receptor Antagonist, NBQX, on Neuron Loss in Dentate Hilus of the Hippocampal Formation after 8, 10, or 12 Min of Cerebral Ischemia in the Rat., Journal of Cerebral Blood Flow and Metabolism., 1997., 17(2):, 147-152., 4. K. Overgaard, T. Sereghy, H. Pederson, G. Boysen..
Literature Reference: Neuroprotection with NBQX and Thrombolysis with RT-PA in Rat Embolic Stroke., Neurological Research., 1993., 15(5):, 344-349., 5. Lees, G.J., W. Leong..
Literature Reference: Differential Effects of NBQX on the Distal and Local Toxicity of Glutamate Agonists Administered Intra-Hippocampally., Brain Research., 1993., 628(1-2):, 1-7..
Bulk Quantity: Readily Available, Please Inquire
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This item can not be ordered online. Please call or email with any queries.
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