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PROLI NONOate, PROLI/NO
[P1009]
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Description: A Nitric Oxide Donor, useful for reliable generation of Nitric Oxide (NO) in vitro or in vivo. Half Life (t1/2) for NO release at 37°C is N.D1.
Half Life (t1/2) for NO release at 22°-25°C is 1.8 seconds1.
Chemical Formula: C5H7N3O4Na2.CH3OH
Chemical Name: : Disodium 1-[2-(Carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2diolate.methanol
Molecular Weight: M.W. 251.1
Solubility: Readily Soluble in Water and Methanol.
Active Product: N
Appearance: White Crystalline Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial. Protect from Moisture.
Storage: -20°C.
Shipping: Express Courier
General Comments: For comprehensive literature review, please call (858) 452-9925.
Literature Reference: 1. Keefer, L.K., R.W. Nims, K.M. Davies, and D.A. Wi., NONOates (1-Substitutes Diazen-1-ium-1,2-diolates) as Nitric Oxide Donors: Convenient Nitric Oxide Dosage Forms., 1996., 298:, 281-293., 2. Smith, D.J.. et al..
Literature Reference: Nitric Oxide-Releasing Polymers Containing the [N(O)NO]- Group., Journal of Medicinal Chemistry., 1996., 39:, 1148-1156., 3. Mooradian, D.l., T.C. Hutsell, L.K. Keefer..
Literature Reference: Nitric Oxide (NO) Donor Molecules: Effects of NO Release Rate on Vascular Smooth Muscle Cell Proliferation In Vitro., Journal of Cardiovascular Pharmacology., 1995., 25(4):, 674-678., 4. Keefer, L.K., et al..
Literature Reference: In Nitrosamines and Related N-Nitroso Compounds: Chemistry and Biochemistry" (R.N. Loeppky and C.J. Michejda eds., American Chemical Society (ACS Symposium Series 553), Washington, D.C.., 1994., 136., 5. Maragos, C.M., J.M. Wang, J.A. Hrabie, J.J. Oppenheim, L.K. Keefer.
Literature Reference: Nitric Oxide / Nucleophile Complexes inhibit the In Vitro Proliferation of A375 Melanoma Cells via Nitric Oxide Release., Cancer Research., 1993., 53(3):, 564-568., 6. Morley, D., L.K. Keefer..
Literature Reference: Nitric Oxide / Nucleophile Complexes: A Unique Class of Nitric Oxide-Based Vasodilators, Journal of Cardiovascular Pharmacology., 1993., 22(Suppl. 7):, S3-S9..
Bulk Quantity: Inquire
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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