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Paclitaxel, Taxus brevifolia
[P1027]
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Description: Anti-tumor agent isolated from the bark of the yew tree. Stabilizes microtubes in their polymerized form, leading to cell death.
Chemical Formula: C47H51NO14
Chemical Name: : Taxol, Baccatin III N-benzyl-beta-phenylisoserine ester
Molecular Weight: M.W. 853.9
Solubility: Soluble in DMSO, Ethanol, Methanol.
CAS Number: CAS [33069-62-4]
Active Product: N
Appearance: White Crystalline Powder
Purity: >97% by TLC, HPLC
Handling: Warning! Toxic. May be Carcinogenic. Wear gloves/mask when handling product. Avoid contact by all modes of exposure.
Storage: -20°C. Protect from light
Shipping: Express Courier
Literature Reference: 1. Merck Index., 12:, 7117.
2.Lu H, Li B, Kang Y, Jiang W, Huang Q, Chen Q, Li L, Xu C.
paclitaxel nanoparticle inhibits growth of ovarian cancer xenografts and enhances lymphatic targeting. Cancer Chemother Pharmacol. May 23, 2006
3. Kakolyris S, Agelidou A, Androulakis N, Tsaroucha E, Kouroussis C, Agelidou M, Karvounis N, Veslemes M, Christophylakis C, Argyraki A, Geroyianni A, Georgoulias V.
Cisplatin plus etoposide chemotherapy followed by thoracic irradiation and paclitaxel (taxol) plus cisplatin consolidation therapy for patients with limited stage small cell lung carcinoma. Lung Cancer. May 20, 2006
4. Peltier S, Oger JM, Lagarce F, Couet W, Benoit JP.
Enhanced Oral paclitaxel (taxol) Bioavailability After Administration of paclitaxel (taxol)-Loaded Lipid Nanocapsules. Pharm Res. May 25, 2006
5.Reck M, von Pawel J, Macha HN, Kaukel E, Deppermann KM, Bonnet R, Ulm K, Hessler S, Gatzemeier U. Efficient palliation in patients with small-cell lung cancer by a combination of paclitaxel etoposide and carboplatin: Quality of life and 6-years'-follow-up results from a randomised phase III trial. Lung Cancer. May 17, 2006.
Bulk Quantity: Inquire, *FOR RESEARCH PURPOSES ONLY*
New pricing for 2008
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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