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Puromycin.Dihydrochloride
[P1033]
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Description: Puromycin is an antibiotic used in molecular biology for selecting mammalian cell lines, which have been transformed by vectors that express puromycin-N-acetyl-transferase. Puromycin, the antibiotic, acts by inhibiting translation by causing premature termination. It does this by binding to the A site in place of tyrosyl-tRNA during transpeptidation.
Chemical Formula: C22H29N7O5.2HCl
Chemical Name: : (S) 3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine,3'-(a-Amino-p-methoxy-hydocinnamamido)-3'-dexoy-N,N-dimethyladenosine.2HCl
Molecular Weight: M.W. 544.5
Solubility: Puromycin is soluble in Water (50mg/ml).
CAS Number: CAS [58-58-2]
Active Product: N
Appearance: White to Off-White Powder
Purity: >98%
Handling: Warning! Toxic. May be Carcinogenic. Wear gloves and mask when handling product. Avoid contact by all modes of exposure.
Storage: Room Temperature.
Shipping: Priority Courier
General Comments: Suggested puromycin concentration for selection is 1.0-30 ug / ml (mammalian). Stock Solutions can be made in Water (5-50 mg / ml). Store solution at -20°C.
Literature Reference: 1. Merck Index., 1996., 12:, 8130..
Bulk Quantity: Readily Available, Inquire for special pricing.
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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