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PI(3,4)P2, di C8 [P1119]
Alternative Product ID: PtdIns-3,4-P2
Description: Water soluble form. Substrate for PIP5K. Inhibited by PI(4,5)P2.
Chemical Formula: C27H53O19P3
Chemical Name: : L-alpha-D-myo-Phosphatidylinositol 3,4-diphosphate
Molecular Weight: 774
Solubility: Soluble in Water.
Active Product: Y
Appearance: Crystalline Solid
Purity: >99%
Handling: Store in Tightly Sealed Vial. Hygroscopic!
Storage: -20°C.
Shipping: Express Courier
Literature Reference: 1. Fruman, D.A., R.E. Meyers, L.C. Cantley., Phosphoinositide Kinases., 1998., 67:, 481-507., 2. Tolias, K.F., L.C. Cantley..
Literature Reference: Pathways for phosphoinositide synthesis., Chem. Phys. lipids., 1999., 98(1-2):, 69-77., 3. Leevers, S.J., B. Vanhaesebroeck, M.D. Waterfield..
Literature Reference: Signalling through phosphoinositide 3-kinases: the Lipids take centre stage., Current Opinion in Cell Biology., 1999., 11(2):, 219-225., 4. T. Maehama, J.E. Dixon..
Literature Reference: PTEN: a Tumour Suppressor that Functions as a Phospholipid Phosphatase., Trends Cell Biol., 1999., 9(4):, 125-128, 5. Wurmser, A.E., J.D. Gary, S.D. Emr..
Literature Reference: Phosphoinositide 3-kinases and their FYVE Domain-Containing Effectors as Regulators of Vacuolar/Lysosomal Membrane Trafficking Pathways., J. Biol. Chem., 1999., 274(14):, 9129-9132..
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