|
|
|
|
|
Pifithrin-alpha
[P1177]
|
Description: Chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Reversibly blocks p53 dependent transcriptional activation and apoptosis.
Chemical Formula: C16H18N2OS . HBr
Chemical Name: : 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide
Molecular Weight: M.W. 367.3
Solubility: Soluble in DMSO.
CAS Number: CAS [63208-82-2]
Active Product: N
Appearance: Off-White Solid
Purity: >95%
Handling: Protect from Light. Unstable in Aqueous Solutions.
Storage: -20°C.
Shipping: Express Courier
Literature Reference: 1. Komarova E.A., A.V. Gudkov., Suppression of p53: a new approach to overcome side effects of antitumor therapy, 2000., 65(1):, 41-48., 2. Komarov P.G., E.A. Komarova..
Literature Reference: A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy., Science., 1999., 285(5434):, 1733-1737., 3. Ferber D..
Literature Reference: Cancer research. A new way to combat therapy side effects. Comment., Science., 1999., 285(5434):, 1653..
Bulk Quantity: Inquire
|
|
|
To ADD this item on your order fill in the fields below and select the 'Add to Order' button. Otherwise select the 'Don't Add' button.
Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
|
|
|
|
|
