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PD 169,316
[P1185]
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Description: Potent, cell Permeable and selective inhibitor of p38 (SAPK2a).
Chemical Formula: C20H13FN4O2
Chemical Name: : 4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
Molecular Weight: M.W. 360.3
Solubility: Soluble in DMSO; slightly Soluble in Methanol. Insoluble in Water, Ethyl Acetate or Diethyl Ether.
Active Product: N
Appearance: Yellow Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial. Protect from Light.
Storage: -20°C.
Shipping: Express Courier
Literature Reference: 1.Cheng, H.F. et al., Role of p38 in the Regulation of Renal Cortical Cyclooxygenase-2 Expression by Extracellular Chloride., 2000., 106(5):, 681-688., 2. Ko, H.W. et al..
Literature Reference: Synergetic Activation of p38 Mitogen-Activated Protein Kinase and Caspase-3-like Proteases for Execution of Calyculin A-induced Apoptosis but not N-methyl-d-aspartate-Induced Necrosis in Mouse Cortical Neurons., J. Neurochem., 2000., 74(6):, 2455-2461..
Bulk Quantity: Inquire
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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