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Monoclonal Antibody to PTEN, Purified, 100ug/100ul
[P1195]
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Description: PTEN plays an important role in the modulation of the 1-phosphatidylinositol 3-kinase pathway. PTEN inhibits downstream functions mediated by PtdIns 3-kinase pathway such as activation of PKB, cell survival and cell proliferation.
Product Data: Clone: 6H2.1. Isotype: Mouse IgG. Specificity: Raised against a fusion protein containing the C-terminal human PTEN sequence. Detects a ~60 kDa band of human and mouse PTENby Western Blot. MAPK. Application: WB, IHC.
Quantity: Purified Monoclonal Antibody to PTEN at concentration: 100ug/100ul
Literature Reference: 1. Cantley, L.C. & B.G. Neel., New Insights into Tumor Suppression: PTEN Suppresses Tumor Formation by Restraining the Phosphoinositide 3-Kinase / AKT Pathway., 1999., 96:, 4240., 2. Maehama, T., & J.E. Dixon..
Literature Reference: PTEN: A Tumour Suppressor that Functions as a Phospholipid Phosphatase., Trends Cell Biol., 1999, 9:, 125., 3. Di Cristofano, A., & P.P. Pandolfi..
Literature Reference: The Multiple Roles of PTEN in Tumor Suppression., Cell., 2000., 100., 387..
Availability: Special Availability, please inquire.
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This item can not be ordered online. Please call or email with any queries.
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