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Beta-Rubromycin [R1118]
Description: A quinone antibiotic that inhibits HIV-1 reverse transcriptase (RT). Cytostatically active against different tumor cell lines. Inhibits Human telomerase.
Chemical Formula: C27H22O12
Molecular Weight: M.W. 538.5
Active Product: N
Shipping: Express Courier
Literature Reference: 1. Ueno, T., Inhibition of human telomerase by rubromycins: implication of spiroketal system of the compounds as an active moiety., 2000., 39(20):, 5995-6002., 2. Goldman, M.E. et al..
Literature Reference: Inhibition of human immunodeficiency virus-1 reverse transcriptase activity by rubromycins: competitive interaction at the template.primer site., Mol Pharmacol., 1990., 38(1):, 20-25., 3. Brockmann, H. et al..
Literature Reference: The structure of rubromycin., Tetrahedron Lett., 1966., 30:, 3525-3530..
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