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L-Thiocitrulline [T1010]
Description: A potent inhibitor of Neuronal and Inducible Nitric Oxide Synthase.
Chemical Formula: C6H13N3O2S
Chemical Name: : 2-Thioureido-L-norvaline
Molecular Weight: M.W. 191.25
Solubility: Soluble in Water, Methanol, and DMSO.
CAS Number: CAS [156719-37-8]
Active Product: N
Appearance: White Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial. Protect from Light and Moisture.
Storage: +4°C.
Shipping: Express Courier
Literature Reference: 1. Narayanan, K., O.W. Griffith., Synthesis of L-Thiocitrulline, L-Homothiocitrulline, and S-Methyl-L-Thiocitrulline: A New Class of Potent Nitric Oxide Synthase Inhibitors, 1994., 37(7):, 885-887., 2. Furfine, E.S., M.F. Harmon, J.E. Paith, R.G. Knowles, M. Salter, R.J. Kiff, C. Duffy et al..
Literature Reference: Selective Inhibition of Neuronal Nitric Oxide Synthase by S-Methyl-L-Thiocitrulline and S-Ethyl-L-Thiocitrulline., Journal of Biological Chemistry., 1994., 269(43):, 26677-26683., 3. Zanzinger, J., J. Czachurski, H. Seller..
Literature Reference: Neuronal Nitric Oxide Reduces Sympathetic Excitability by Modulation of Central Glutamate Effects in Pigs., Circulation Research., 1997., 80(4):, 565-571., 4. Joly, G.A., K. Narayanan, O.W. Griffith, R.G. Kilbourn..
Literature Reference: Characterization of the Effects of Two New Arginine / Citrulline Analogs on Constitutive and Inducible Nitric Oxide Synthases in Rat Aorta., British Journal of Pharmacology., 1995., 115(3):, 491-497., 5. Frey, C., K. Narayanan, K. McMillan, L. Spack, S.S. Gross, B.S. Masters, O.W. Griffith..
Literature Reference: L-Thiocitrulline. A Stereospecific, Heme-Binding Inhibitor of Nitric Oxide Synthases, Journal of Biological Chemistry., 1994., 269(42):, 26083-26091..
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