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Wortmannin,Penicillium wortmanni
[W1022]
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Description: Wortmannin is a fungal metabolite that specifically inhibits phosphatidylinositol 3-kinase (PI-3), mitogen-activated protein kinase (MAPK) and myosin light-chain kinase (MLCK).
Chemical Formula: C23H24O8
Chemical Name:
Molecular Weight: M.W. 428.4
Solubility: Wortmannin is Soluble in Methanol and DMSO.
CAS Number: CAS [19545-26-7]
Boiling Point / Melting Point: BP/MP: 240°C
Active Product: Y
Appearance: Off-White to Pale Yellow Solid
Purity: >98%
Handling: Hygroscopic. Protect from Light and Moisture. Store in Tightly Sealed Vial.
Storage: -20°C.
Shipping: Express Courier
Literature Reference: 1. Merck Index., 1996., 12:, 10188., 2. Okbayasu, R., K. Suetomi, R.L. Ullrich..
Literature Reference: Wortmannin Inhibits Repair of DNA Double-Strand Breaks in Irradiated Normal Human Cells., Radiation Research., 1998., 58(9):, 440-445., 3. Carnero, A., J.C. Lacal..
Literature Reference: Wortmannin, An Inhibitor of Phosphatidyl-inositol 3-Kinase, Induces Ococyte Maturation Through a MPF-MAPK-Dependent Pathway., FEBS Letters., 1998., 422(2):, 155-159., 4. Park, Y.C., C.H. Lee, H.S. Kang, H.T. Chung, H.D. Kin..
Literature Reference: Wortmannin, A Specific Inhibitor of Phosphatidylinositol-#-3Kinase, Inhances LPS-Induced NO Production from Murine Peritoneal Macrophages., Biochemical and Biophysical Research Communications., 1997., 240(3):, 692-696..
Bulk Quantity: Available, Please Inquire
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Note: All products sold by A.G. Scientific are for Laboratory or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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