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YC-1 [Y1000]
Description: A direct activator of soluble Guanylyl Cyclase (sGC), independent of Nitric Oxide.
Chemical Formula: C19H16N2O2
Chemical Name: : 3-(5'-hydroxymethyl-2'furyl)-1-benzyl indazole
Molecular Weight: M.W. 304.4
Solubility: Soluble in Chloroform, Methanol, and DMSO.
Active Product: N
Appearance: Off-White to Yellow Solid
Purity: >98%
Handling: Store in Tightly Sealed Vial.
Storage: +4°C.
Shipping: Express Courier
Literature Reference: 1. Mulsch, A., J. Bauersachs, A. Schafer, J.P. Stasch, R. Kast, R. Busse., Effect of YC-1, An NO-Independent, Superoxide-Sensitive Stimulator of Soluble Guanylyl Cyclase, On Smooth Muscle Responsiveness to Nitrovasodilators., 1997., 120(4):, 681-689., 2. Teng, C.M., C.C. Wu, F.N. Ko, F.Y. Lee, S.C. Kuo..
Literature Reference: YC-1, A Nitric Oxide-Independent Activator of Soluable Guanylate Cyclase, Inhibits Platelet-Rich Thrombosis in Mice., European Journal of Pharmacology., 1997., 320(2-3):, 161-166., 3. Ko, F.N., C.C. Wu, S.C. Kuo, F.Y. Lee, C.M. Teng..
Literature Reference: YC-1, A Novel Activator of Platelet Guanylate Cyclase., Blood., 1994., 84(12):, 4226-4233..
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