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A23187, Mixed Calcium-Magnesium Salt

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A23187, Mixed Calcium-Magnesium Salt

Formula: C56 H66 Ca N4 O12 . C56 H66 Mg N4 O12 MW: 2038.69 Appearance: White to Light Yellow Solid Purity: 98%
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A-1128 5 mg
$57.83
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10 mg
$128.80
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A23187 has antifungal properties, its antibacterial activities are targeted towards gram positive bacteria. The divalent cation ionophore activity of A23187 is utilized in laborotories to to increase intracellular Ca2+ levels in intact cells.A23187 also induces apoptosis in some cells (e.g. mouse lymphoma cell line, or S49, and Jurkat cells) and prevents it in others (e.g. cells dependent on interlukin 3 that have had the factor withdrawn). Used in cell activation experiments when calcium dose-response data are not required. Molar ratio Ca:Mg (1:1).

 

Additional Information

Product # A-1128
Chemical Name BIS[[2-[[(3R,4R,6R,7R,9R,10S)-3,7,9-TRIMETHYL-10-[(1S)-1-METHYL-2-OXO-2-(1H-PYRROL-2-YL)ETHYL]-5,11-DIOXASPIRO[5.5]UNDECAN-4-YL]METHYL]-1,3-BENZOXAZOLE-4-CARBONYL]OXY]CALCIUM; BIS[[2-[[(3R,4R,6R,7R,9R,10S)-3,7,9-TRIMETHYL-10-[(1S)-1-METHYL-2-OXO-2-(1H-PYR
Formula C56 H66 Ca N4 O12 . C56 H66 Mg N4 O12
MW 2038.69
Appearance White to Light Yellow Solid
Purity 98%
Solubility Soluble in DMSO, Chloroform, and Ethylacetate.
Boiling Point 710.3±55.0 °C at 760 mmHg
Storage Temp +4°C
Use A compound used in cell activation

Additional Information

MDL Number MFCD00213962
ChemACX X6952231-2
InChI InChI=1S/4C28H34N2O6.Ca.Mg/c4*1-15-10-11-28(17(3)13-16(2)26(36-28)18(4)25(31)20-8-6-12-29-20)35-22(15)14-23-30-24-19(27(32)33)7-5-9-21(24)34-23;;/h4*5-9,12,15-18,22,26,29H,10-11,13-14H2,1-4H3,(H,32,33);;/q;;;;2*+2/p-4/t4*15-,16-,17-,18-,22-,26+,28-;;/m1111../s1
SMILES C[C@@H]1CC[C@@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)c3ccc[nH]3)C)C)O[C@@H]1Cc4nc5c(cccc5o4)C(=O)O[Mg]OC(=O)c6cccc7c6nc(o7)C[C@@H]8[C@@H](CC[C@]9(O8)[C@@H](C[C@H]([C@H](O9)[C@H](C)C(=O)c1ccc[nH]1)C)C)C.C[C@@H]1CC[C@@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)

Additional Information

GHS Pictograms
UN #'S UN 3462
PACKING GROUP III
Handling Warning.Toxic. Wear gloves/mask when handling product. Avoid contact by all means of exposure. Protect from Light

Additional Information

Certificate of Analysis 1 A-1128_A-1128,_A7534.pdf

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A23187, Mixed Calcium-Magnesium Salt

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