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Product Description
Physiologically active metabolite of the immunosuppressive drug leflunomide (Cat. No.1972-10, 50). Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-κB activation in a dose- and time-dependent manner. Also inhibits the activity of COX-2 in vitro and in vivo.
Additional Information
| Product Number | A-2176 |
| CAS # | 108605-62-5 |
| Chemical Name | N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide |
| Chemical Formula | C12H9F3N2O2 |
| Appearance | White solid |
| Molecular Weight | 270.21 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO |
| Storage Temp | -20°C |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
