Cycloheximide - 1x5 g$80.00
You're currently on:
An anti-neoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis.
Potent anti-tumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes.
Attached are a few published references from researchers who have used our Actinomycin D product. We respectfully thank them for their trust in our product. Inquire for a full reference list.
MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS: Respiratory Syncytial Virus Inhibits Lung Epithelial Na+ Channels by Up-regulating Inducible Nitric-oxide Synthase, Weifeng Song, et al., J. Biol. Chem., Mar 2009; 284: 7294 - 7306.
ANTIVIRAL AGENTS: Heat Stress Cognate 70 Host Protein as a Potential Drug Target against Drug Resistance in Hepatitis B Virus, Yu-Ping Wang, et al., Antimicrob. Agents Chemother., May 2010; 54: 2070 - 2077.
INFLAMMATION AND IMMUNOPHARMACOLOGY: Lipopolysaccharide Induces Epithelium- and Prostaglandin E2-Dependent Relaxation of Mouse Isolated Trachea through Activation of Cyclooxygenase (COX)-1 and COX-2, Rowan W. Balzary and Thomas M. Cocks, J. Pharmacol. Exp. Ther., May 2006; 317: 806 - 812.
CELLULAR AND MOLECULAR: A Trimeric Anti-HER2/neu ScFv and Tumor Necrosis Factor- Fusion Protein Induces HER2/neu Signaling and Facilitates Repair of Injured Epithelia, Tzu-Hsuan Huang and Sherie L. Morrison, J. Pharmacol. Exp. Ther., Mar 2006; 316: 983 - 991.
MECHANISMS OF SIGNAL TRANSDUCTION: Nongenotropic, Anti-Apoptotic Signaling of 1,25(OH)2-Vitamin D3 and Analogs through the Ligand Binding Domain of the Vitamin D Receptor in Osteoblasts and Osteocytes: MEDIATION BY Src, PHOSPHATIDYLINOSITOL 3-, AND JNK KINASES, Anthony M. Vertino, et al., J. Biol. Chem., Apr 2005; 280: 14130 - 14137.
|CAS #||CAS [50-76-0]|
|Chemical Name||Isolated from Streptomyces sp.|
|Alternative Name||Actinomycin IV, Actinomycin C1, Dactinomycin|
|Appearance||Red to orange powder|
|Merck Index||Merck Index: 12.2867.1996|
|Molecular Weight||M.W. 1255.42|
|Solubility||Soluble in DMSO: 1mg/mL, ethanol.|
STILL COMPARING & NOT READY TO BUY? CLICK HERE FOR 10 % OFF YOUR NEXT PURCHASE.
Require bulk price at a PREFERRED DISCOUNT$$$? CLICK HERE.
Follow our latest scientific offerings WITH OUR DAILY BLOG. CLICK HERE.
All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
Double click on above image to view full picture