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Adriamycin Hydrochloride

CAS: 25316-40-9 Formula: C27 H29 N O11 . Cl H MW: 579.983 Appearance: Orange Red Solid Purity: 99%
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A-1442 25 mg
$273.48
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Adriamycin is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later approved for human therapeutic use as an anti-tumor agent for the treatment of a wide range of cancers. Adriamycin has also been reported to exhibit anti-HIV and actibacterial activity. The mode of action of Adriamycin is thought to be due to intercalation of DNA and inhibition of nucleic acid synthesis.

Additional Information

Synonyms Doxorubicin, 14-Hydroxydaunomycin, Adriacin, Adriblastin, Caelyx, Dox, Doxil, Farmiblastina, FI 106, K 1039, KW 125, NSC 123127
Product # A-1442
CAS # 25316-40-9
Chemical Name (8S,10S)-10-[(3-AMINO-2,3,6-TRIDEOXY-ALPHA-LYXO-HEXOPYRANOSYL)OXY]-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-5,12-NAPHTHACENEDIONE HYDROCHLORIDE
Formula C27 H29 N O11 . Cl H
MW 579.983
Appearance Orange Red Solid
Purity 99%
Solubility Soluble in water, methanol, DMSO, DMF with moderate ethanol solubility
Melting Point 203.9-205 °C
Boiling Point 810.3 °C at 760 mmHg
Storage Temp -20°C
Therapeutic Area Oncological Disorders
Use It is used as anticancer agent

Additional Information

MDL Number MFCD00077757
ChemACX X1014352-9
InChI InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
SMILES C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](Cc3c2c(c4c(c3O)C(=O)c5cccc(c5C4=O)OC)O)(C(=O)CO)O)N)O.Cl

Additional Information

GHS Pictograms
RTECS QI9295900

Additional Information

Certificate of Analysis 1 A-1442_A-1442,_B1962.pdf
Certificate of Analysis 2 A-1442_A-1442,_B1675.pdf
E-Brochure Antibiotics Brochure

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Adriamycin Hydrochloride

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