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AG 490

AG 490
Product Number: A-1164
Price Price Qty Add to Cart
1x10 mg
$78.00
1x50 mg
$310.00

Product Description

Selectively inhibits CDK2 activation leading to a potent cell cycle arrest at late G1 and S phase. Cell permeable inhibitor of JAK-2 tyrosine kinase. Does not significantly inhibit other kinases, such as Lck, Lyn, Btk, Syk or Src. Blocks IL-7 induced JAK kinase activity in T cells (JAK-1, JAK-3) and the consequent phosphorylation of PI-3 kinase. Valuable tool for studying the cellular role of JAK kinases in signal transduction.

Additional Information

Product Number A-1164
CAS # CAS [133550-30-8]
Chemical Name N-Benzyl-3,4-dihydroxy-benzylidenecyanoacetamide α-Cyano-(3,4-dihydroxy)-]N-benzylcinnamamide
Chemical Formula C17H14N2O3
Alternative Name Tyrphostin B42, Tyrphostin AG 490
Appearance Yellow solid
Molecular Weight M.W. 294.3
Purity Purity: ≥98%
Solubility Soluble in DMSO (30mg/ml), DMF (40mg/ml) or 100% ethanol (10mg/ml).
Storage Temp -20°C

Notice

All products sold by A.G. Scientific are strictly for Laboratory purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use. 
 

AG 490

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