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Cell-permeable. A potent and specific protein arginine N-methyltransferase (PRMTs) inhibitor (IC50 = 8.8 μM for human PRMT1 and 3.0 μM for yeast Hmt1p ). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Also acts as a HIV-1 RT polymerase inhibitor (IC50 = 5.0 μM).
|Chemical Name||Arginine N-methyltransferase inhibitor-1|
|Purity||≥98% by NMR|
|Solubility||DMSO or Ethanol or water|
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