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Antibiotics
Image courtesy of Public Library of Science publication. The In Vivo Kinetics of RNA Polymerase II Elongation during Co-Transcriptional Splicing from researchers at Bar-Ilan University, Ramat Gan, Israel, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, and Ecole Normale Supérieure, Institut de Biologie de l'ENS. AG Scientific’s Puromycin was used to select for B-globin constructs.
AG SCIENTIFIC Antibiotics are for Research use only.
To help speed your search for the right Antibiotics Download the free E-Guide to Antibiotics (click here)
The use of antibiotics in retaining the purity for a particular selection factor in a population of cells is well documented. The success in fermentation & sysnthesis has allowed AG Scientific a leadership position as the preferred supplier to Universities and Businesses worldwide.
Here are a few of our more successful materials:
Hygromycin B is a standard antibiotic that selects for exclusively hygromycin resistant cells. HYGRO FAQS
Puromycin is an antibiotic that inhibits translation via premature chain termination; it is toxic to both prokaryotic and eukaryotic cells.
Blasticidin kills both eukaryotic and prokaryotic cells by inhibiting peptide bond formation. Resistance to blasticidin occurs with expression of one of three genes: bsr, bls, or BDS.
G418 inhibits polypeptide synthesis in prokaryotic and eukaryotic cells and is structurally related to gentamycin.
FK 506 Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines
17-AAG is an ansamycin antibiotic which acts as an anti-tumor agent.
Cycloheximide Cycloheximide is an antibiotic produced by Streptomyces griseus, and acts as an inhibitor of protein synthesis in eukaryotes but not prokaryotes
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