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Antibiotics

Antibiotics are essential in retaining the purity for a particular selection factor in a population of cells. Resistance to a variety of harmful antibiotics that interfere with desirable protein synthesis can be conferred through the use of cell culture products. AG Scientific has had particular success in the manufacture and supply of the following antibiotics.

  • Hygromycin B is a standard antibiotic that selects for exclusively hygromycin resistant cells. 
  • Puromycin is an antibiotic that inhibits translation via premature chain termination; it is toxic to both prokaryotic and eukaryotic cells. 

  • Blasticidin kills both eukaryotic and prokaryotic cells by inhibiting peptide bond formation. Resistance to blasticidin occurs with expression of one of three genes: bsr, bls, or BDS. 

  • G418 inhibits polypeptide synthesis in prokaryotic and eukaryotic cells and is structurally related to gentamycin. 

 

 

AG Scientific delivers quality assured antibiotics for gene selection and cell culture directly to scientists, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.

 

  • Product Number: L-1163

    Beta-Lactamase, E.C.3.5.2.6, penicillin amido-beta-lactam hydrolase, isolated from the organism, Bacillus cereus 569/H9 Beta Lactamase is used to destroy/remove Beta-Lactam antibiotics.

  • Product Number: R-1118

    A quinone antibiotic that inhibits HIV-1 reverse transcriptase (RT). Cytostatically active against different tumor cell lines. Inhibits Huma

  • Product Number: R-2473

    γ-Rubromycin isolated from Streptomyces sp. consists of a

  • Product Number: A-1026

    Aphidicolin is a reversibl

  • Product Number: P-1655

    (+)-Pyripyropene A is Isolated from </

  • Product Number: L-2170

    Cell-permeable. An analog of thalidomide that was originally found based on its ability to effectively inhibit tumor necrosis factor product

  • Product Number: A-2394

    (S)-(+)-Ascochin is isolated from Ascochyta sp.

  • Product Number: D-1113

    Antimetabolite of phosphatidylinositol-3-phosphate. An inhibitor of cancer cell colony formation.

  • Product Number: A-1256

    17-AAG is an ansamycin antibiotic which acts as an anti-tumor

  • Product Number: A-1298

    A semi-synthetic derivate of Geldanamcyin, 17-DMAG binds to Hsp90 and alters its function. A water soluble & cell-permeable analog of Ge

  • Product Number: B-1265

    Boswellic acid derivative, which shows anti-tumor and anti-inflammatory activities. Potent non-redox, noncompetitive 5-lipoxygenase and topo

  • Product Number: A-1130

    Nonfluorescent calcium ionophore used as a calibration standard for determining cytoplasmic calcium ions by fluorescent probes.  Inquire

  • Product Number: C-1472

    Chloride Ionophore.  Special order item, inquire for pricing & lead time from product stock.

  • Product Number: C-2402

    5-Hydroxy-2-methyl-4-chromanone isolated from Nodulisporium

  • Product Number: A-1132

    7-Amino-Actinomycin D is a Fluorescent DNA Stain. Binds Single strand

  • Product Number: R-2002

    Product is high affinity ligand for retinoid X receptor (RXR). Able t

  • Product Number: A-1020

    A23187 is a widely used ionophore. It has the ability to inc

  • Product Number: A-1128

    Used in cell activation experiments when calcium dose-response data are not required. Molar ratio Ca:Mg~1:1.Inquire for bulk pricing.

  • Product Number: A-2176

    A77 1726 physiologically active metabolite of the immunosuppressive drug leflunomide (Cat. No.1972-10, 50). A77 1726 Inhibits the activity o

  • Product Number: A-2178

    Potent inhibitor of PARP-1 and PARP-2 (potency ≤5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibiti

  • Product Number: A-2387

    Acetomycin isolated from Streptomyces ramulosus is novel antitumor ag

  • Product Number: A-1272

    Source: Produced in HEK 293 cells. The non-homologous (aa16-45) and collagen domain of human ACRP30 (aa 45-108) are fused at the N-terminus

  • Product Number: A-1022

    An anti-neoplastic antibiotic that inhibits cell proliferation by for

  • Product Number: A-1120

    Antibiotic that demonstrates anti-tumor activity. Also unique anti-bacterial agent. Inhibitor of leucine aminopeptidase.

  • Product Number: A-1442

    Adriamycin is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces spec

  • Product Number: A-1416

    Displays broad spectrum of antibacterial activities. Anti-neoplastic compound, inhibiting several cancer cell lines. Associated with contrac

  • Product Number: A-2388

  • Product Number: A-2389

     Isolated from fungus A 6239

  • Product Number: A-2390

  • Product Number: A-1286

    Membrane permeabilizing Antibiotic. Increases [32P] incorporation int

  • Product Number: A-1710

    Molds belonging to the genus Alternaria areubiquitous are common contaminants of foods & feeds. Since the molds can grow at low

  • Product Number: L-2379

     

  • Product Number: A-1430

    Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=10.2 µM) and Raji cell

  • Product Number: A-2185

    Amiodarone.HCl is a non-selective ion channel blocker with broad fungicidal activity. Amiodarone induces an immediate influx of Ca2+

  • Product Number: A-1077

    A polyene anti-fungal antibiotic that non-specifically induces loss of low molecular weight substances from cells. Binds to stero

  • Product Number: A-1414

    Ampilillin Sodium Salt manufacturedto meet USP standards, assay

  • Product Number: A-1049

    Anisomycin is a pyrrolidine antibiotic, that acts as an anti-fungal

  • Product Number: A-2393

    Antibiotic PF 1052 isolated from Phoma sp. is an antibacteri

  • Product Number: A-1712

    This sterile solution is composed of penicillin (10000-12000 units/ml), streptomycin (10000-12000 ug/ml)

  • Product Number: A-1268

    Induces apoptosis, which is not prevented by the presence of bcl-2. Inhibits mitochondrial electron transport specifically between cytochrom

  • Product Number: A-1264

    Potent inhibitor of histone deacetylase (HDAC) (IC50=700pM).

  • Product Number: A-1108

    A MAP Kinase inhibitor; and a selective inhibitor of CK2.    Chemopreventive and anti-tumor properties - inhibits proliferation of malignant tumor cells by G2/M arrest.  Apoptosis inducer.  Inquire for availability of other sizes. 

  • Product Number: A-1258

    An ethyl analog of FK506 with strong immunosuppressant properties. Acts by binding to immunophilins, especially macrophilin-12. It appears t

  • Product Number: A-2395

    Antibiotic: Shows nematicidal, insecticidal, antibacterial a

  • Product Number: A-1438

    Antibiotic. Potent and specific inhibitor of mitochondrial complex II (succinate-ubiquinone oxidoreductase).  Synthetic, originally isolate

  • Product Number: A-1270

    Strong antibiotic activity against gm-positive bacteria and cytotoxicity. Shows inhibitory effects on cellular adhesion and anaphylatoxin re

  • Product Number: A-1760

    Aureothricin is an antibiotic. Aureothricin is more hydrophobic analog of the antibiotic thiolutin with selective anti-tumor activity. Aureo

  • Product Number: A-1700

    Source: Islolated from marine mussel. Activator of JNK (c-Jun-N-terminal kinase). Cellular growth inhibitor and inducer of cytoskeletal alte

  • Product Number: B-2396

    Bacimethrin is isolated from Streptomyces albus.

  • Product Number: B-1261

    Antibiotic that demonstrates anti-bacterial action in vitro against a variety of gram-positive and a few gram-negative organisms.