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Cytochalasin D- STRUCTURE-ANTI-FUNGAL-ACTIN FILAMENTS

CYTOCHALASIN D
Product Number: C-1070

        

Details

Cytochalasin D is a cell-permeable fungal toxin, 10-fold more effective than Cytochalasin B.Binds to barbed end of actin filaments, inhibiting the association and dissociation of subunits.Does not inhibit monosaccharide transport across cell membranes.Reported to exhibit antitumor activity, and induce apoptosis.

Additional Information

Alternate Name/Synonyms Zygosporin A
MSDS Documentation:
COA Documentation:
MP/BOILING POINT 712.1±60.0 °C at 760 mmHg
CHEMACX X1009686-7
Handling Protect from Light Store in Tightly Sealed Vial Warning.Toxic.
Package ID Refrigerated
MDL NUMBER MFCD00077706
PACKING GROUP II
INCHI InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
SMILES C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3Cc4ccccc4)C)O
UN #'S UN 1544
USE Cytochalasin D is a member of the class of mycotoxins known as cytochalasins
Product Number C-1070
CAS # 22144-77-0
Chemical Name (7S,13E,16S,18R,19E,21R)-21-(ACETYLOXY)-7,18-DIHYDROXY-16,18-DIMETHYL-10-PHENYL[11]CYTOCHALASA-6(12),13,19-TRIENE-1,17-DIONE
Chemical Formula C30H37NO6
Appearance White Solid
Handling Protect from Light Store in Tightly Sealed Vial Warning.Toxic.
Melting Point 255-260°C
Merck Index 12.2859.1996
Molecular Weight 507.63
Purity 97%
RTECS GZ4850000
Solubility Soluble in 100% ethanol, acetone or ethyl acetate. Insoluble in water.
Storage Temp -20°C

Cytochalasin D- STRUCTURE-ANTI-FUNGAL-ACTIN FILAMENTS

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