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Cytochalasin D- STRUCTURE-ANTI-FUNGAL-ACTIN FILAMENTS

CYTOCHALASIN D
Product Number: C-1070

        

Details

Cytochalasin D is a cell-permeable fungal toxin, 10-fold more effective than Cytochalasin B.Binds to barbed end of actin filaments, inhibiting the association and dissociation of subunits.Does not inhibit monosaccharide transport across cell membranes.Reported to exhibit antitumor activity, and induce apoptosis.

Additional Information

Alternate Name/Synonyms Zygusporium mansonii, Zygosporin A
MSDS Documentation:
COA Documentation:
MP/BOILING POINT 255-260°C / 712.1±60.0 °C at 760 mmHg
CHEMACX X1009686-7
Handling Protect from Light Store in Tightly Sealed Vial Warning.Toxic.
Package ID Refrigerated
MDL NUMBER MFCD00077706
PACKING GROUP II
Peptide sequence Not Applicable
INCHI InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
SMILES C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3Cc4ccccc4)C)O
UN #'S UN 1544
USE Cytochalasin D is a member of the class of mycotoxins known as cytochalasins
Product Number C-1070
CAS # 22144-77-0
Chemical Name (7S,13E,16S,18R,19E,21R)-21-(ACETYLOXY)-7,18-DIHYDROXY-16,18-DIMETHYL-10-PHENYL[11]CYTOCHALASA-6(12),13,19-TRIENE-1,17-DIONE
Chemical Formula C30H37NO6
Appearance White Solid
Handling Protect from Light Store in Tightly Sealed Vial Warning.Toxic.
Merck Index 12.2859.1996
Molecular Weight 507.63
Purity 97%
RTECS GZ4850000
Solubility CH2Cl2: Clear and colorless solution at 10 mg/ml, Soluble in Ethanol
Storage Temp -20°C

Cytochalasin D- STRUCTURE-ANTI-FUNGAL-ACTIN FILAMENTS

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