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Antimycin A3

CAS: 522-70-3 Formula: C26H36N2O9 MW: 520.6 Appearance: White solid Purity: >98% by HPLC
Hazardous

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A-2621 1 mg
$260.06
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5 mg
$910.22
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*Please inquire the availability for this product. Antimycin A3 is a homologue of the antimycin complex, first isolated in 1958 from Streptomyces blastimyceticus and co-produced with antimycin A4. Antimycin A3 is a more polar analogue of A1 and A2. Like all antimycins, antimycin A3 is a potent inhibitor of respiration by inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A3 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active. Lack of availability of the individual antimycin components has hindered greater understanding of the common and unique molecular targets of the components of the antimycin complex.

Additional Information

Synonyms Blastmycin, NSC 58239
Product # A-2621
CAS # 522-70-3
Chemical Name [(2R,3S,6S,7R,8R)-8-BUTYL-3-[(3-FORMAMIDO-2-HYDROXYBENZOYL)AMINO]-2,6-DIMETHYL-4,9-DIOXO-1,5-DIOXONAN-7-YL] 3-METHYLBUTANOATE
Formula C26H36N2O9
MW 520.6
Appearance White solid
Purity >98% by HPLC
Melting Point 170 °C
Boiling Point 745.5 °C at 760 mmHg
Storage Temp -20°C
Therapeutic Area Infectious Diseases
Use Antimycin A3 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active

Additional Information

MDL Number MFCD00869273
InChI InChI=1S/C26H36N2O9/c1-6-7-9-18-23(37-20(30)12-14(2)3)16(5)36-26(34)21(15(4)35-25(18)33)28-24(32)17-10-8-11-19(22(17)31)27-13-29/h8,10-11,13-16,18,21,23,31H,6-7,9,12H2,1-5H3,(H,27,29)(H,28,32)/t15-,16+,18-,21+,23+/m1/s1
SMILES CCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)c2cccc(c2O)NC=O)C)OC(=O)CC(C)C

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RTECS NY1502900
UN #'S UN 2811
PACKING GROUP II
HAZARD CLASS Class 6.1

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Antimycin A3

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