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Product Description
A MAP Kinase inhibitor; and a selective inhibitor of CK2. Chemopreventive and anti-tumor properties - inhibits proliferation of malignant tumor cells by G2/M arrest. Apoptosis inducer. Inquire for availability of other sizes.
Attached are a few published references from researchers who have used our Apigenin product. We respectfully thank them for their trust in our product. Inquire for a full reference list.
REGULAR ARTICLES: Suppression of Constitutive and Tumor Necrosis Factor -Induced Nuclear Factor (NF)-B Activation and Induction of Apoptosis by Apigenin in Human Prostate Carcinoma PC-3 Cells: Correlation with Down-Regulation of NF-B-Responsive Genes, Sanjeev Shukla and Sanjay Gupta, Clin. Cancer Res., May 2004; 10: 3169 - 3178.
RESEARCH ARTICLES: TARGETS: Molecular targets for apigenin-induced cell cycle arrest and apoptosis in prostate cancer cell xenograft, Sanjeev Shukla and Sanjay Gupta, Mol. Cancer Ther., Apr 2006; 5: 843 - 852.
FJ EXPRESS ARTICLES: Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice, Sanjeev Shukla, Anil Mishra, et al., FASEB J, Dec 2005; 19: 2042 - 2044.
Additional Information
COA Documentation: |
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| Product Number | A-1108 |
| CAS # | CAS [520-36-5] |
| Chemical Name | 4',5,7-Trihydroxyflavone |
| Chemical Formula | C15H10O5 |
| Appearance | Yellow to Brown Solid |
| Melting Point | MP: 345-350°C |
| Molecular Weight | M.W. 270.2 |
| Purity | Purity: >97% |
| Solubility | Soluble in DMSO, Potassium Hydroxyde (diluted); slightly soluble in (hot) 100% Ethanol. Insoluble in Water. |
| Storage Temp | Room Temperature |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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