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Product Description
A semi-synthetic derivate of Geldanamcyin, 17-DMAG binds to Hsp90 and alters its function. A water soluble & cell-permeable analog of Geldanamycin (G-1047) and 17-AAG (A-1256), 17-DMAG binds to the APTase site of human Hsp90a with high affinity, has cytotoxic activity against many cancer cell lines, and acts as angiogenesis inhibitor.
Additional Information
COA Documentation: |
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| Product Number | A-1298 |
| Chemical Formula | C32H48N4O8 |
| Alternative Name | 17-dimethylaminoethylamino-17-demethoxy-geldanamycin |
| Appearance | Purple powder |
| Molecular Weight | M.W. 616.8 |
| Preparation | Clear purple solution at 10mg 17DMAG in 1ml of Methanol, or 25mg 17DMAG in 1ml DMSO |
| Purity | Purity: >98% by TLC |
| Solubility | Soluble in DMSO, Methanol, Ethanol |
| Storage Temp | -20°C |
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