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Epoxomicin, Synthetic - 1x100 µg$195.00
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Product Description
Cell permeable inhibitor of γ-secretase (IC50=115 nM for total β-amyloid, IC50=200 nM for β-amyloid 1-42). Does not inhibit presenilinase. Antagonizes Notch signaling through inhibition of Notch processing. DAPT treatment can influence hematopoietic cell fate decisions and enhances neuronal differentiation in embryonic stel cell-derived embryoid bodies independent of sonic hedgehog (Shh) signaling.
Additional Information
COA Documentation: |
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| Product Number | D-1210 |
| CAS # | 208255-80-5 |
| Chemical Name | N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester |
| Chemical Formula | C23H26F2N2O4 |
| Appearance | White to Off-white solid |
| Molecular Weight | M.W. 432.5 |
| Preparation | Aliquots should be stored at -20C, Stock solutions stable up to 3 months. |
| Purity | Purity:>98% |
| Solubility | Soluble in100% Ethanol, DMSO, or Dichloromethane |
| Storage Temp | -20°C |
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