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Cathepsin Inhibitors

Catehpsins belong to the papain superfamily of lysosomal cysteine proteases. The cathepsin inhibitor induces rapid apoptotic death in human cancer cell lines. Cathepsin S inhibitor induces autophagy and mitochondrial apoptosis in human glioblastoma cells. Cathepsin B and L inhibitors suppress normal lysosomal degradation and the processing of lysosomal enzyme, leading to lysosomal dysfunction. So it result in consequent cell death in pancreatic β–cells.

AG Scientific can ship FedEx directly to your lab, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.

  1. Antipain Hydrochloride, CAS 37691-11-5

    Antipain Hydrochloride, CAS 37691-11-5

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    A-1413 37691-11-5 5 mg
    $61.92
    10 mg
    $121.78
  2. Calpain Inhibitor

    Calpain Inhibitor

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-2213 20 l (10mM)
    $123.84
  3. Calpain inhibitor I, CAS# 110044-82-1, Calpain Inhibitor I  is Cell-permeable, peptide aldehyde inhibitor of calpain I (Ki=190nM), calpain II (C-1259)(Ki=150nM), cathepsin B, cathepsin L (Ki=0.5nM) and other neutral cysteine proteases

    Calpain Inhibitor I, MG-101

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    P-1153 110044-82-1 5 mg
    $98.04
    25 mg
    $319.92
  4. Calpain Inhibitor III

    Calpain Inhibitor III

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-1549 88191-84-8 10 mg
    $56.76
    25 mg
    $144.48
    50 mg
    $221.88
  5. Caspase-1 Inhibitor Z-YVAD-FMK

    Caspase-1 Inhibitor Z-YVAD-FMK

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-2226 20 L
    $123.84
    100 L
    $123.84
  6. Cathepsin B&amp, L Inhibitor Z-Phe-Phe-FMK

    Cathepsin B&amp, L Inhibitor Z-Phe-Phe-FMK

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-2259 20 ul (10mM)
    $170.28
  7. Cathepsin G Inhibitor

    Cathepsin G Inhibitor

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-2260 429676-93-7 1 mg
    $170.28
  8. E-64

    E-64

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    E-2030 66701-25-5 5 mg
    $46.45
    25 mg
    $185.75
  9. G-418.Sulfate, Sterile solution | Aminoglycoside antibiotic | g418 solution is an aminoglycoside antibiotic used as a selective agent of transfected mammalian, yeast, plant and bacteria cells. Offered by A.G. Scientific

    G-418.Sulfate, Sterile-Filtered Solution

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    G-1035 108321-42-2 10 ml
    $35.09
    50 ml
    $123.84
    5x10 ml
    $139.32
    100 ml
    $232.20
  10. Leupeptin, Hemisulfate

    Leupeptin, Hemisulfate

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    L-1165 103476-89-7 5 mg
    $27.00
    10 mg
    $75.00
    25 mg
    $99.60
    50 mg
    $255.00
    100 mg
    $355.00
    500 mg
    $1,150.00
  11. Pepstatin A, Inhibitor of aspartic proteases

    Pepstatin A, Inhibitor of aspartic proteases

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    P-1519 26305-03-3 5 mg
    $34.10
    25 mg
    $98.00
  12. three protease inhibitors with selective specificity for the inhibition of cysteine proteases, including calpains, cathepsins and papain

    Protease Inhibitor Cocktail VIII

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    P-1548 1 ml
    $61.92
  13. Z-FA-FMK

    Z-FA-FMK

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    Z-2486 105637-38-5 1 mg
    $77.40
    5 mg
    $273.48