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Catehpsins belong to the papain superfamily of lysosomal cysteine proteases. The cathepsin inhibitor induces rapid apoptotic death in human cancer cell lines. Cathepsin S inhibitor induces autophagy and mitochondrial apoptosis in human glioblastoma cells. Cathepsin B and L inhibitors suppress normal lysosomal degradation and the processing of lysosomal enzyme, leading to lysosomal dysfunction. So it result in consequent cell death in pancreatic β–cells.
AG Scientific can ship FedEx directly to your lab, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.