Granzymes

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Granzymes at a glance

Michael Bots and Jan Paul Medema. Granzymes at a glance. J. Cell Sci, 2006; 119: 5011 - 5014.

Differential expression of the granzymes A, K and M and perforin in human peripheral blood lymphocytes

Britta Bade, Heidrun Elise Boettcher, et al. Differential expression of the granzymes A, K and M and perforin in human peripheral blood lymphocytes. Int. Immunol, 2005; 17: 1419 - 1428.

Differential expression of the granzymes A, K and M and perforin in human peripheral blood lymphocytes

Javier A. Carrero, Hector Vivanco-Cid, et al. Granzymes Drive a Rapid Listeriolysin O-Induced T Cell Apoptosis. J. Immunol, 2008; 181: 1365 - 1374.

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Product Number	G-1073
Chemical Name	Ac-Glu-Ser-Met-Asp-CHO
Chemical Formula	C₁₉H₃₀N₄O₁₀S
Alternative Name	Caspase-8 Inhibitor, Granzyme B Inhibitor (Aldehyde), Caspase-6, Caspase-10
Appearance	White Lyophilized Powder
Molecular Weight	M.W. 506.5
Purity	Purity: ≥99% (HPLC)
Solubility	Soluble in distilled water.
Storage Temp	-20°C

Ac-ESMD-CHO Product Number: G-1073
Price	Price	Qty	Add to Cart
1x1 mg	$58.00
1x5 mg	$220.00

Product Number	G-1081
Chemical Name	Ac-Ile-Glu-Thr-Asp-AMC
Chemical Formula	C₃₁H₄₁N₅O₁₂
Alternative Name	Caspase-8, Granzyme B substrate (Fluorogenic), Caspase-10
Appearance	White Lyophilized Powder. TFA salt.
Molecular Weight	M.W. 675.7
Purity	Purity: ≥98% (HPLC)
Solubility	Soluble in DMSO. Dilute with buffer, pH 7.5.
Storage Temp	-20°C

Ac-IETD-AMC Product Number: G-1081
Price	Price	Qty	Add to Cart
1x1 mg	$42.00
1x5 mg	$120.00

Product Number	G-1071
Chemical Name	Ac-Ile-Glu-Thr-Asp-CHO
Chemical Formula	C₂₁H₃₄N₄O₁₀
Alternative Name	Caspase-8 Inhibitor, Caspase-10 Inhibitor , Granzyme B Inhibitor (Aldehyde)
Appearance	White Lyophilized Powder
Molecular Weight	M.W. 502.5
Purity	Purity: ≥97% (HPLC)
Solubility	Soluble in DMSO. Dilute with buffer (pH 7.5).
Storage Temp	-20°C

COA Documentation: G-1071, A8794, r01 Ac-IETD-CHO Product Number: G-1071
Price	Price	Qty	Add to Cart
1x1 mg	$67.00
1x5 mg	$260.00

Product Number	G-1085
Chemical Name	Ac-Ile-Glu-Thr-Asp-pNA
Chemical Formula	C₂₇H₃₈N₆O₁₂
Alternative Name	Caspase-8 Substrate (Chromogenic), Caspase-10, Granzyme B Substrate, Chromogenic
Appearance	White to Yellow Powder.
Molecular Weight	M.W. 638.6
Purity	Purity: >98% (HPLC)
Solubility	Soluble in DMSO, Dilute with buffer, pH 7.0-7.5.
Storage Temp	-20°C

COA Documentation: G-1085, B1008 G-1085, B1008A, r01 Ac-IETD-pNA Product Number: G-1085
Price	Price	Qty	Add to Cart
1x1 mg	$28.00
1x5 mg	$100.00

Product Number	C-1249
Chemical Name	Z-Ile-Glu(OMe)-Thr-Asp(OMe)-fluoromethylketone
Chemical Formula	C₃₀H₄₃FN₄O₁₁
Alternative Name	Z-IE(OMe)TD(OMe)-FMK
Appearance	White to Off-White Solid.
Molecular Weight	M.W. 654.7
Preparation	Stock solutions should be divided into aliquots and stored at -20°C.
Purity	Purity: ≥95%
Solubility	Soluble in DMSO.
Storage Temp	-20°C

Caspase Inhibitor, Z-IE(OMe)TD(OMe)-FMK Product Number: C-1249
Price	Price	Qty	Add to Cart
1x1 mg	$0.00
1x5 mg	$0.00

Product Number	E-2317
CAS #	N/A
Chemical Name	Q-Val-Asp-OPh; Quinolyl-Val-Asp-OPh
Chemical Formula	C₂₆H₂₅F₂N₃O₆
Appearance	Liquid
Molecular Weight	513.49
Purity	>95% by HPLC
Solubility	N/A
Storage Temp	-20°C

EZSolution™ Q-VD-OPh Product Number: E-2317
Price	Price	Qty	Add to Cart
1x1 mg	$195.00

Product Number	E-2318
CAS #	N/A
Chemical Name	Q-Val-Glu-OPh; Quinolyl-Val-Glu-OPh
Chemical Formula	C₂₇H₂₇F₂N₃O₆
Appearance	Liquid
Molecular Weight	527.19
Purity	>95% by HPLC
Solubility	N/A
Storage Temp	-20°C

EZSolution™ Q-VD-OPh, Negative Control Product Number: E-2318
Price	Price	Qty	Add to Cart
1x1 mg	$165.00

Product Number	F-1160
CAS #	[82956-11-4]
Chemical Formula	C21H25N5O8S2
Alternative Name	FUT-175, Nafamostat Mesylate
Appearance	White to off white
Merck Index	14, 6350
Molecular Weight	539.6
Purity	>98%
RTECS	DG2736000
Solubility	Soluble in DMSO or water

MSDS Documentation: F-1160, Futhan, MSDS COA Documentation: F-1160, B1683 F-1160, C1201 F-1160, C1202 Futhan Product Number: F-1160
Price	Price	Qty	Add to Cart
1x10 mg	$70.00
1x50 mg	$285.00

Product Number	G-1079
Chemical Name	Boc-Ala-Ala-Asp-SBzl
Chemical Formula	C₂₂H₃₁N₃O₇S
Alternative Name	Boc-AAD-SBzl
Appearance	White to off-white Crystalline Powder
Molecular Weight	M.W. 481.6
Purity	Purity: ≥95% (HPLC)
Solubility	Soluble in DMSO.
Storage Temp	-20°C

Granzyme B Substrate, BAADT Product Number: G-1079
Price	Price	Qty	Add to Cart
1x1 mg	$120.00
1x5 mg	$410.00

Product Number	G-1059
Appearance	Liquid. Concentration: 1mg/ml. Purified antibody in PBS containing 0.02% sodium azide.
Preparation	Stable for at least 6 months when stored at +4°C undiluted.
Purity	Purity: ≥95% (SDS-PAGE)
Storage Temp	+4°C

COA Documentation: G-1059, B1218 Monoclonal Antibody to-Granzyme B, Human, B18.1 Product Number: G-1059
Price	Price	Qty	Add to Cart
1x100 ug	$305.00
1x100 FITC Tests	$335.00

Product Number	G-1029
Appearance	Liquid. Antibody dissolved in 1% BSA containing 0.1% sodium azide.
Preparation	Long Term Storage: -20°C.
Storage Temp	+4°C

Monoclonal Antibody to-Granzyme B, Human, GrB7 Product Number: G-1029
Price	Price	Qty	Add to Cart
1x50 μg	$625.00

Product Number	P-1383
Alternative Name	Monoclonal Antibody to Proteinase Inhibitor 9 (human) (PI9-17)
Appearance	Liquid. Antibody in serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide.
Preparation	Long Term Storage: -20°C.
Storage Temp	+4°C

COA Documentation: P-1383, A8881 Monoclonal Antibody to-Proteinase Inhibitor 9 (Human) (PI9-17) Product Number: P-1383
Price	Price	Qty	Add to Cart
1x125 μg	$420.00

Product Number	G-1077
Chemical Name	Z-Ile-Glu(OMe)-Thr-Asp(OMe)-FMK
Chemical Formula	C₃₀H₄₃FN₄O₁₁
Alternative Name	Caspase-8 Inhibitor (FMK), Caspase-10, Granzyme B Inhibitor (FMK)
Appearance	White to off-white solid
Molecular Weight	M.W. 654.7
Preparation	Solutions can store at -20C
Purity	Purity:> 90% (HPLC)
Solubility	Soluble in DMSO
Storage Temp	-20°C

COA Documentation: G-1077, C1135 Z-IE(OMe)TD(OMe)-FMK Product Number: G-1077
Price	Price	Qty	Add to Cart
1x1 mg	$220.00
1x5 mg	$710.00

Product Number	G-1083
Chemical Name	Z-Ile-Glu-Thr-Asp-pNA
Chemical Formula	C₃₃H₄₂N₆O₁₃
Alternative Name	Caspase-8 Substrate (Chromogenic), Caspase-10, Granzyme B Substrate (Chromogenic)
Appearance	White Lyophilized Powder
Molecular Weight	M.W. 730.7
Purity	Purity: ≥99% (HPLC)
Solubility	Soluble in Water.
Storage Temp	-20°C

Z-IETD-pNA Product Number: G-1083
Price	Price	Qty	Add to Cart
1x1 mg	$22.00
1x5 mg	$83.00

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