Mitochondrial Pathway

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Mitochondrial Pathway

Mitochondrial kinase signalling pathways in myocardial protection from ischaemia/reperfusion-induced necrosis

Tetsuji Miura, Masaya Tanno, et al. Mitochondrial kinase signalling pathways in myocardial protection from ischaemia/reperfusion-induced necrosis. Cardiovasc Res, 2010; 88: 7 - 15.

Cell Stress Gives a Red Light to the Mitochondrial Cell Death Pathway

M. Eugenia Guicciardi and Gregory J. Gores. Cell Stress Gives a Red Light to the Mitochondrial Cell Death Pathway. Sci. Signal, 2008; 1: pe9.

Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1{alpha}-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer

Stephen L. Archer, Mardi Gomberg-Maitland, et al. Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1{alpha}-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. Am J Physiol Heart Circ Physiol, 2008; 294: H570 - H578.

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Product Number	A-2185
CAS #	19774-82-4
Chemical Name	2-Butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride
Chemical Formula	C₂₅H₂₉I₂NO₃
Appearance	White to off-white solid
Molecular Weight	681.77
Purity	≥98% by TLC
Solubility	H₂O (50 mg/ml)
Storage Temp	-20°C

Amiodarone Hydrochloride Product Number: A-2185
Price	Price	Qty	Add to Cart
1x100 mg	$65.00
1x500 mg	$255.00

Product Number	A-1268
CAS #	CAS [1397-94-0 ]
Appearance	White to faint yellow powder.
Merck Index	Merck Index: 13.720 (Antimycin A1) & 721 (Antimycin A3)
Solubility	Soluble in 100% ethanol (50mg/ml).
Storage Temp	-20°C

COA Documentation: A-1268, B1864 A-1268, B1536A Antimycin A Product Number: A-1268
Price	Price	Qty	Add to Cart
1x10 mg	$38.00

Product Number	C-1355
Alternative Name	Polyclonal Antibody to Caspase-9 (active)
Appearance	Liquid. 100µg of affinity-purified antibody in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide.
Preparation	Long Term Storage: -80°C. Avoid freeze/thaw cycles.
Storage Temp	-20°C

COA Documentation: C-1355, A8927 Antiserum to-Capsase-9 (Active) Product Number: C-1355
Price	Price	Qty	Add to Cart
1x100 μg	$280.00

Product Number	A-1438
CAS #	CAS[119509-24-9]
Chemical Name	3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinone
Chemical Formula	C₁₅H₂₁CI₂NO₅
Appearance	White to off White Powder
Molecular Weight	M.W.366.2
Purity	Purity: ≥95% (HPLC)
Solubility	Soluble in DMSO, methanol or 100% ethanol; insoluble in water.
Storage Temp	-20°C

COA Documentation: A-1438, C1207 Atpenin A5, Penicillium sp. Product Number: A-1438
Price	Price	Qty	Add to Cart
1x250 µg	$177.00

Product Number	B-1053
CAS #	CAS [11076-19-0]
Chemical Formula	C₂₈H₃₈O₇.₃NH₃
Appearance	White Solid
Melting Point	MP: 50-60°C
Merck Index	Merck Index: 13.1323.2001
Molecular Weight	M.W. 537.7
Purity	Purity: >98%
Solubility	Reconstitute to 1 mg/ml with distilled water
Storage Temp	-20ºC

COA Documentation: B-1053, A10021 B-1053, B1890 Bongkrekic Acid.3NH3 Product Number: B-1053
Price	Price	Qty	Add to Cart
1x100 μg	$124.00

Product Number	C-1109
CAS #	CAS [518-75-2]
Chemical Name	4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid
Chemical Formula	C₁₃H₁₄O₅
Alternative Name	Antimycin
Appearance	Off-White to Yellow Crystals
Melting Point	MP: 170°C
Merck Index	Merck Index: 13.2351.
Molecular Weight	M.W. 250.25
Purity	Purity: >98%
Solubility	Soluble in Dichloromethane.
Storage Temp	+4°C

COA Documentation: C-1109, C1081 Citrinin Product Number: C-1109
Price	Price	Qty	Add to Cart
1x5 mg	$85.00
1x10 mg	$200.00

Product Number	C-2268
CAS #	168425-64-7
Chemical Name	2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one
Chemical Formula	C₁₆H₁₅N₃O₂
Appearance	White to off-white solid
Molecular Weight	281.31
Purity	≥97% by HPLC
Solubility	DMSO (10 mM) or EtOH (5 mM)
Storage Temp	+4°C

Compound 401 Product Number: C-2268
Price	Price	Qty	Add to Cart
1x5 mg	$165.00

Product Number	C-1199
CAS #	CAS [59865-13-3]
Chemical Formula	C₆₂H₁₁₁N₁₁O₁₂
Alternative Name	Ciclosporin, Cyclosporin A, Ramihyphin A
Appearance	White powder
Merck Index	Merck Index: 13.2781.2001
Molecular Weight	M.W. 1202.6
Purity	Purity: ≥98%
Solubility	Soluble in DMSO (25mg/ml), methanol, 100% ethanol (25mg/ml), or acetone. Insoluble in water
Storage Temp	-20°C

COA Documentation: C-1199, A8587, r01 Cyclosporin A, Fusarium solani Product Number: C-1199
Price	Price	Qty	Add to Cart
1x100 mg	$55.00
1x500 mg	$215.00

Product Number	C-1365
Storage Temp	+4°C

Cytochrome c ELISA Kit, Human Product Number: C-1365
Price	Price	Qty	Add to Cart
1x1 Kit	$695.00

Product Number	C-1367
Storage Temp	-20°C

Cytochrome c Releasing Apoptosis Assay Kit Product Number: C-1367
Price	Price	Qty	Add to Cart
1x100 tests	$585.00

Product Number	C-2282
CAS #	23541-50-6
Chemical Name	Daunomycin hydrochloride
Chemical Formula	C₂₇H₂₉NO₁₀
Appearance	Orange-red powder
Molecular Weight	563.98
Purity	>95%
Solubility	H₂O or MeOH
Storage Temp	+4°C

COA Documentation: C-2282, D1036 Daunorubicin.HCl Product Number: C-2282
Price	Price	Qty	Add to Cart
1x10 mg	$75.00
1x50 mg	$225.00
1x500 mg	$1,450.00

Product Number

D-1143

CAS #

CAS [6956-96-3]

Chemical Name

2,3-Dimethoxy-1,4-naphthoquinone. Soluble in DMSO, Acetone, Chloroform or Methanol.

Chemical Formula

C₁₂H₁₀O₄

Appearance

Crystalline Solid

Molecular Weight

M.W. 218.2

Purity

Purity: ≥99%

Solubility

COA Documentation: D-1143, B1131, r02 D-1143, C1212 DMNQ Product Number: D-1143
Price	Price	Qty	Add to Cart
1x5 mg	$75.00
1x10 mg	$115.00
1x25 mg	$250.00

F16 Product Number: F-1166
Price	Price	Qty	Add to Cart
1x5 mg	$30.00
1x25 mg	$105.00

FCCP Product Number: C-1616
Price	Price	Qty	Add to Cart
1x10 mg	$79.00
1x50 mg	$314.00

Isozyme-Selective-Akt Inhibitor \| CAS#612847-09-3 \| Inhibits Akt1/Akt2 activity Product Number: A-1714
Price	Price	Qty	Add to Cart
1x1 mg	$125.00

COA Documentation: J-1090, A8052 JC-1.Iodide Product Number: J-1090
Price	Price	Qty	Add to Cart
1x5 mg	$265.00

MitochondriaCytosol Fractionation Kit Product Number: C-1369
Price	Price	Qty	Add to Cart
1x1 kit	$440.00

COA Documentation: S-1114, B1215 S-1114, B1244 Monoclonal Antibody to α-Synuclein, Human (15G7) Product Number: S-1114
Price	Price	Qty	Add to Cart
1x500 ul	$185.00
1x1 ml	$260.00

Monoclonal Antibody to-Bax (2D2), Human Product Number: B-1213
Price	Price	Qty	Add to Cart
1x100 μg	$280.00

COA Documentation: B-1211, A8373 Monoclonal Antibody to-Bax (6A7), Universal Product Number: B-1211
Price	Price	Qty	Add to Cart
1x100 μg	$280.00

Monoclonal Antibody to-Bcl 10 (Carmen-1) Product Number: B-1203
Price	Price	Qty	Add to Cart
1x100 μg	$325.00

COA Documentation: B-1239, B1917 B-1239, A9701 Monoclonal Antibody to-BIM S/EL/L (14A8) Product Number: B-1239
Price	Price	Qty	Add to Cart
1x100 ug	$345.00

COA Documentation: B-1241, A8466 Monoclonal Antibody to-BimL (5E5) Product Number: B-1241
Price	Price	Qty	Add to Cart
1x100 ug	$350.00

COA Documentation: B-1231, A8151 Monoclonal Antibody to-BMF (12E10) Product Number: B-1231
Price	Price	Qty	Add to Cart
1x100 ug	$347.00

COA Documentation: B-1233, A9999 Monoclonal Antibody to-BMF (9G10) Product Number: B-1233
Price	Price	Qty	Add to Cart
1x100 ug	$320.00

Monoclonal Antibody to-Noxa (Human) (114C307) Product Number: N-1123
Price	Price	Qty	Add to Cart
1x100 μg	$325.00

Necrosis Inhibitor-2 Product Number: N-1221
Price	Price	Qty	Add to Cart
1x1 mg	$103.00
1x5 mg	$309.00

COA Documentation: N-1223, D1059 Necrosis Inhibitor-5 Product Number: N-1223
Price	Price	Qty	Add to Cart
1x1 mg	$130.00
1x5 mg	$305.00

COA Documentation: N-1227, C1157 Necrostatin-1 Product Number: N-1227
Price	Price	Qty	Add to Cart
1x5 mg	$61.00
1x25 mg	$248.00

Necrostatin-7 Product Number: N-1225
Price	Price	Qty	Add to Cart
1x5 mg	$130.00
1x25 mg	$495.00

MSDS Documentation: N-1103, Nigericin, MSDS COA Documentation: N-1103, A10008 N-1103, C1189 Nigericin, Sodium Salt \| CAS [28643-80-3] \| Polyether ionophore Product Number: N-1103
Price	Price	Qty	Add to Cart
1x5 mg	$66.00
1x10 mg	$115.00

MSDS Documentation: O-1063, Oligomycin A, MSDS COA Documentation: O-1063, B1882 O-1063, C1083 O-1063, C1153 Oligomycin A, Streptomyces diastatochromogenes. Product Number: O-1063
Price	Price	Qty	Add to Cart
1x1 mg	$40.00
1x5 mg	$166.00

COA Documentation: O-1064, A9216 Oligomycin B, Streptomyces diastatochromogenes. Product Number: O-1064
Price	Price	Qty	Add to Cart
1x1 mg	$40.00
1x5 mg	$166.00

COA Documentation: O-1066, A8563 Oligomycin C, Streptomyces diastatochromogenes. Product Number: O-1066
Price	Price	Qty	Add to Cart
1x1 mg	$295.00

COA Documentation: O-1060, B1266 Oligomycin, Streptomyces diastatochromogenes Product Number: O-1060
Price	Price	Qty	Add to Cart
1x5 mg	$79.00
1x10 mg	$135.00

COA Documentation: P-1474, C1082 P-1474, B1957 Piericidin A, Streptomyces sp. \| CAS[2738-64-9] \| Antibiotics Product Number: P-1474
Price	Price	Qty	Add to Cart
1x2 mg	$130.00
1x10 mg	$410.00

Protein G, Recombinant Product Number: P-2413
Price	Price	Qty	Add to Cart
1x1 mg	$65.00
1x5 mg	$195.00
1x10 mg	$335.00
1x100 mg	$1,995.00
1x1 g	$9,995.00

Protein L, Recombinant Product Number: P-2414
Price	Price	Qty	Add to Cart
1x1 mg	$105.00
1x5 mg	$325.00
1x10 mg	$525.00
1x100 mg	$3,950.00

Reprogramming Cocktail Set II (1000X), Sterile-Filtered Product Number: S-2140
Price	Price	Qty	Add to Cart
1x1 ml	$195.00
1x5 ml	$695.00
5x1 ml	$725.00

COA Documentation: R-2420, C1339 Rocaglamide Product Number: R-2420
Price	Price	Qty	Add to Cart
1x100 ug	$345.00

Stem Cell Fate Regulator Set I Product Number: S-2146
Price	Price	Qty	Add to Cart
1x1 set	$475.00

Stem Cell Fate Regulator Set II Product Number: S-2124
Price	Price	Qty	Add to Cart
1x1 set	$950.00

Stem Cell Fate Regulator Set III Product Number: S-2126
Price	Price	Qty	Add to Cart
1x1 set	$345.00

Stem Cell Fate Regulator Set IV Product Number: S2128
Price	Price	Qty	Add to Cart
1x1 set	$375.00

Stem Cell Fate Regulator Set V Product Number: S-2130
Price	Price	Qty	Add to Cart
1x1 set	$435.00

Stem Cell Fate Regulator Set VI Product Number: S-2132
Price	Price	Qty	Add to Cart
1x1 set	$645.00

Stem Cell Fate Regulator Set VII Product Number: S-2134
Price	Price	Qty	Add to Cart
1x1 set	$845.00

StemBoostReprogramming Cocktail Set I (1000X), Sterile-Filtered Product Number: S-2142
Price	Price	Qty	Add to Cart
1x1 ml	$195.00
1x5 ml	$695.00
5x1 ml	$725.00

MSDS Documentation: T-1016, Tunicamycin, MSDS COA Documentation: T-1016, B1694A T-1016, B1694 Tunicamycin \| CAS#11089-65-9 Product Number: T-1016
Price	Price	Qty	Add to Cart
1x10 mg	$140.00
1x50 mg	$555.00

MSDS Documentation: V-1013, Valinomycin, MSDS.pdf COA Documentation: V-1013, B1795.pdf V-1013, C1131.pdf V-1013, C1155.pdf Valinomycin Product Number: V-1013
Price	Price	Qty	Add to Cart
1x100 mg	$126.00
1x1 g	$910.00

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