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Mitochondrial Pathway

Apoptosis in mitochondria is the best known intrinsic apoptosis pathway that begins when injury occurs within a cell. The Bcl-2 family of proteins regulate apoptosis by controlling the release of caspases activators from mitochondria. Damage to the cellular DNA by toxins, free radicals, or radiation induce changes in the1 inner mitochondrial membrane permeability. The anti-apoptotic proteins Bcl-2,Bcl-x, Bcl-xL , Bcl-XS, Bcl-w and BAG reside in the outer mitochondrial wall and inhibit cytochrome c release. The pro-apoptotic proteins Bcl-10, Bak, Bad, Bid, Bax, Bik, and Bim reside in the cytosol but translocate to mitochondria following death signaling, where they promote the release of cytochrome c.

AG Scientific can ship FedEx directly to your lab, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.

  1. Amiodarone Hydrochloride

    Amiodarone Hydrochloride

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    A-2185 19774-82-4 100 mg
    $67.08
    500 mg
    $263.16
  2. Antimycin A

    Antimycin A

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    A-1268 1397-94-0 10 mg
    $40.45
  3. Antiserum to-Capsase-9 (Active)

    Antiserum to-Capsase-9 (Active)

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-1355 100 μg
    $288.96
  4. ATPENIN CAS 119509-24-9 ATPENIN CAS 119509-24-9 Atpenin A5 has cardioprotective effects

    Atpenin A5, Penicillium sp.

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    A-1438 119509-24-9 250 ug
    $188.86
  5. bongkrekic inhibits permeability transition pore, Mitochondrial membrane potential

    Bongkrekic Acid

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    B-1053 11076-19-0 100 ug
    $136.00
  6. Citrinin,  CIT

    Citrinin, CIT

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-1109 518-75-2 5 mg
    $104.44
    10 mg
    $239.63
  7. Compound 401

    Compound 401

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-2268 168425-64-7 5 mg
    $170.28
  8. Cyclosporin A, Fusarium solani

    Cyclosporin A, Fusarium solani

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-1199 59865-13-3 100 mg
    $56.76
    500 mg
    $221.88
    1 g
    $407.64
  9. Cytochrome c ELis a Kit, Human

    Cytochrome c ELis a Kit, Human

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-1365 1 Kit
    $717.24
  10. Cytochrome c Releasing Apoptosis Assay Kit

    Cytochrome c Releasing Apoptosis Assay Kit

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-1367 100 Tests
    $603.72
  11. Daunorubicin | CAS 23541-50-6 | Anti-cancer agent | AG Scientific

    Daunorubicin Hydrochloride

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-2282 23541-50-6 10 mg
    $77.40
    50 mg
    $232.20
    500 mg
    $1,496.40
  12. FCCP

    FCCP

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-1616 370-86-5 10 mg
    $134.16
    50 mg
    $460.07
  13. Isozyme-Selective-Akt Inhibitor

    Isozyme-Selective-Akt Inhibitor

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    A-1714 612847-09-3 1 mg
    $129.00
  14. MitochondriaCytosol Fractionation Kit

    MitochondriaCytosol Fractionation Kit

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-1369 1 Kit
    $454.08
  15. Monoclonal Antibody to-Bax (2D2), Human

    Monoclonal Antibody to-Bax (2D2), Human

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    B-1213 100 μg
    $298.25
  16. Monoclonal Antibody to-Bax (6A7), Universal

    Monoclonal Antibody to-Bax (6A7), Universal

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    B-1211 100 μg
    $298.25
  17. Monoclonal Antibody to-Bcl 10 (Carmen-1)

    Monoclonal Antibody to-Bcl 10 (Carmen-1)

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    B-1203 100 μg
    $335.40
  18. Monoclonal Antibody to-BimL (5E5)

    Monoclonal Antibody to-BimL (5E5)

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    B-1241 100 ug
    $325.08
  19. Monoclonal Antibody to-BMF (12E10)

    Monoclonal Antibody to-BMF (12E10)

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    B-1231 100 ug
    $335.50
  20. Monoclonal Antibody to-BMF (9G10)

    Monoclonal Antibody to-BMF (9G10)

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    B-1233 100 ug
    $325.08
  21. Monoclonal Antibody to-Noxa (Human) (114C307)

    Monoclonal Antibody to-Noxa (Human) (114C307)

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    N-1123 100 μg
    $335.40
  22. Necrosis Inhibitor-2

    Necrosis Inhibitor-2

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    N-1221 1 mg
    $106.30
    5 mg
    $318.89
  23. Necrosis Inhibitor-5

    Necrosis Inhibitor-5

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    N-1223 1 mg
    $134.16
    5 mg
    $314.76
  24. Necrostatin-1

    Necrostatin-1

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    N-1227 4311-88-0 5 mg
    $62.95
    25 mg
    $255.94
  25. Necrostatin-7

    Necrostatin-7

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    N-1225 351062-08-3 5 mg
    $134.16
    25 mg
    $510.84
  26. Nigericin, Sodium Salt,Polyether ionophore

    Nigericin, Sodium Salt,Polyether ionophore

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    N-1103 28643-80-3 5 mg
    $68.11
    10 mg
    $118.68
  27. Oligomycin | CAS [14104-19-9] | Antibiotics | Inhibits membrane bound mitochondrial ATPases,  Induces Apoptosis. Offered by A.G. Scientific.

    Oligomycin

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    O-1060 1404-19-9 10 mg
    $139.32
  28. Oligomycin A mitochondrial ATPases Inhibitor, Oligomycin A lysosome acidification

    Oligomycin A, Streptomyces diastatochromogenes.

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    O-1063 579-13-5 1 mg
    $42.62
    5 mg
    $176.78
  29. Oligomycin B | CAS [11050-94-5] | Inhibitor mitochondrial ATPase | A.G. Scientific

    Oligomycin B, Streptomyces diastatochromogenes.

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    O-1064 1105-94-5 1 mg
    $41.28
    5 mg
    $171.31
  30. Oligomycin C, Streptomyces diastatochromogenes.

    Oligomycin C, Streptomyces diastatochromogenes.

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    O-1066 11053-72-5 1 mg
    $304.44
  31. Piericidin A, Streptomyces sp.

    Piericidin A, Streptomyces sp.

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    P-1474 2738-64-9 5 mg
    $984.53
  32. Protein G, Recombinant

    Protein G, Recombinant

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    P-2709 1 mg
    $67.08
    5 mg
    $201.24
    10 mg
    $345.72
    100 mg
    $2,058.84
    1 g
    $10,314.84
  33. Protein L, Recombinant

    Protein L, Recombinant

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    P-2414 1 mg
    $108.36
    5 mg
    $335.40
    10 mg
    $541.80
    100 mg
    $4,076.40
  34. Reprogramming Cocktail Set II (1000X), Sterile-Filtered | A.G. Scientific | PD0325901

    Reprogramming Cocktail Set II (1000X), Sterile-Filtered

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2140 1 ml
    $201.24
    5 ml
    $717.24
    5x1 ml
    $748.20
  35. Rocaglamide

    Rocaglamide

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    R-2420 84573-16-0 100 ug
    $356.04
  36. PD-184352, CAS [212631-79-3], Potent, selective and non-competitive inhibitor of MEK 1 (aka MKK 1). Novel inhibitors & stem cell reagents offered by A.G. Scientific

    Stem Cell Fate Regulator Set I

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2146 1 Set
    $490.20
  37. STRUCTURE, CAS [301836-41-9], Acts as an ALK 5 INHIBITOR, Novel stem cell inhibitors offered by A.G. Scientific

    Stem Cell Fate Regulator Set II

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2124 1 Set
    $980.40
  38. Stem Cell Fate Regulator Set III

    Stem Cell Fate Regulator Set III

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2126 1 Set
    $356.04
  39. Stem Cell Fate Regulator Set IV

    Stem Cell Fate Regulator Set IV

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S2128 See under the individual product 1 set
    $387.00
  40. Stem Cell Fate Regulator Set V

    Stem Cell Fate Regulator Set V

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2130 1 Set
    $448.92
  41. Stem Cell Fate Regulator Set VI

    Stem Cell Fate Regulator Set VI

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2132 1 Set
    $665.64
  42. Stem Cell Fate Regulator Set VII

    Stem Cell Fate Regulator Set VII

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2134 1 Set
    $872.04
  43. StemBoostReprogramming Cocktail Set I (1000X), Sterile-Filtered | A.G. Scientific, Inc. | CHIR99021

    StemBoostReprogramming Cocktail Set I (1000X), Sterile-Filtered

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2142 1 ml
    $201.24
    5 ml
    $717.24
    5x1 ml
    $748.20
  44. Tunicamycin CAS 11089-65-9 Glycoprotein Antibiotic useful in glycoprotein researc

    Tunicamycin

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    T-1016 11089-65-9 10 mg
    $144.48
    50 mg
    $572.76
  45. Valinomycin | CAS 2001-95-8 | Potassium ionophore

    Valinomycin

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    V-1013 2001-95-8 100 mg
    $130.00
    1 g
    $940.00
  46. Venturicidin B| CAS [33538-72-6] | FO ATP synthase inhibitor Venturicidin

    Venturicidin B, Streptomyces sp.

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    V-1070 33538-72-6 0.25 mg
    $230.00
    1 mg
    $750.00