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Product Description
Cell-permeable. A potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC50 = 10 nM). Displays excellent selectivity against many other kinases including Btk, Fyn, Itk, Lyn and Src up to concentrations of 4.7 µM. Shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models.
Additional Information
| Product Number | B-2195 |
| CAS # | N/A |
| Chemical Name | 2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide, HCl |
| Chemical Formula | C20H18N6O3.HCl |
| Appearance | Yellow solid |
| Molecular Weight | 426.86 |
| Purity | ≥98% by HPLC |
| Solubility | H2O (30 mg/ml) DMSO (2 mg/ml) |
| Storage Temp | -20°C |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
