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Widely used fluorescent indicator of intracellular pH. It has a pKa of 7.0, which is perfectly matched to the normal range of cytoplasmic pH. It's fluorescence excitation profile is also pH dependent.
Attached are a few published references from researchers who have used our BCECF product. We respectfully thank them for their trust in our product. Inquire for a full reference list.
COMPLICATIONS: Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic db/db Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1, Louisa M. Villeneuve, Mitsuo Kato, et al., Diabetes, Nov 2010; 59: 2904 - 2915.
|Chemical Name||2',7'-bis-(2-carboxyethyl) -5-(and-6)-carboxyfluorescein, acetoxymethyl ester|
|Molecular Weight||M.W. 821|
|Preparation||Store solutions good for 6 months.|
|Solubility||Soluble in DMSO.|
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