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A biotinylated derivative of the tetrapeptide inhibitor ASTD-FMK, which acts as a competitive inhibitor for the cleavage site of pro-EMAP II (Endothelial monocyte-activating polypeptide). EMAPII, which is a proinflammatory cytokine and a chemoattractant for monocytes, is specifically processed and released upon the induction of apoptosis in cultured cells.
|Chemical Name||Biotinyl-Ala-Ser-Thr-DL-Asp-Fluoromethylketone; Biotinyl-ASTD-Fluoromethylketone|
|Purity||≥95% by HPLC|
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