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Angiogenesis

Angiogenesis is the process of building new vasculature and is inherently coordinated with building new tissue. Increased angiogenesis is a distinguishing characteristic of cancer growth, as it indicates a tumor is developing or has developed its own blood supply. AG Scientific supplies a variety of reagents that can identify or inhibit angiogenesis.  Our most popular are:

• Thalidomide is an angiogenesis inhibitor, it inhibits TNF-alpha biosynthesis.

• 17-AAGis an ansamycin antibiotic which binds with a high affinity into the ATP binding pocket in Hsp90 and induces the degradation of proteins.

• Fumagillin is an inhibitor of endothelial cell proliferation and is currently being investigated as potential treatment of intestinal microsporidiosis.

• Geldanamycin is a benzoquinone ansamycin antibiotic which binds to Hsp90 (Heat Shock Protein 90) and alters it function.

AG Scientific delivers quality assured reagents directly to scientists, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.

  

  1. (+/-)-Thalidomide

    (+/-)-Thalidomide

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    T-1020 50-35-1 100 mg
    $87.50
    500 mg
    $341.47
  2. (-)-Epigallocatechin gallate

    (-)-Epigallocatechin gallate

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    E-2002 989-51-5 50 mg
    $96.04
  3. (R,S)-Lenalidomide

    (R,S)-Lenalidomide

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    L-2170 191732-72-6 25 mg
    $58.69
    100 mg
    $165.40
  4. 17-AAG

    17-AAG

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    A-1256 75747-14-7 500 ug
    $39.70
    1 mg
    $56.88
    5 mg
    $147.79
  5. 17DMAG

    17DMAG

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    A-1298 467214-20-6 1 mg
    $53.35
    5 mg
    $138.72
  6. 2-Phthalimidino-glutaric acid

    2-Phthalimidino-glutaric acid

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    P-1187 5 mg
    $44.81
    25 mg
    $176.07
  7. Anacardic Acid

    Anacardic Acid

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    A-2186 16611-84-0 5 mg
    $73.63
    25 mg
    $275.31
  8. Bleomycin Sulfate

    Bleomycin Sulfate

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    B-1269 9041-93-4 10 mg
    $266.77
  9. Borrelidin CAS 7184-60-3 anti-angiogenic cell cycle arrest

    Borrelidin

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    B-1260 7184-60-3 1 mg
    $335.84
  10. Ciprofloxican

    Ciprofloxican

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-2376 85721-33-1 25 g
    $72.57
  11. COMP, Rat: Angiopoietin-1, Soluble, Human, Recombinant

    COMP, Rat: Angiopoietin-1, Soluble, Human, Recombinant

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    A-1304 10 ug
    $467.39
    50 ug
    $1,195.14
  12. Cytochalasin E, Aspergillus clavatus

    Cytochalasin E, Aspergillus clavatus

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-1197 36011-19-5 1 mg
    $55.48
    5 mg
    $203.81
    10 mg
    $353.20
  13. Fumagillin

    Fumagillin

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    F-1028 23110-15-8 1 mg
    $48.60
    5 mg
    $85.82
    10 mg
    $165.44
    25 mg
    $320.54
  14. Geldanamycin | CAS [30562-34-6] | binds HSP90 | anti-tumor activity | A.G.Scientific, binds to Hsp90 (Heat Shock Protein 90) and exhibits potent antitumor activity

    Geldanamycin

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    G-1047 30562-34-6 500 ug
    $43.43
    1 mg
    $58.94
    5 mg
    $108.57
    10 mg
    $206.80
  15. GM6001

    GM6001

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    G-1231 142880-36-2 Inquire 5 mg
    $0.00
    1 mg
    $103.40
  16. Herbimycin A, Streptomyces Hygroscopicus

    Herbimycin A, Streptomyces Hygroscopicus

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    H-1050 70563-58-5 100 ug
    $155.10
    1 mg
    $501.49
  17. Mithramycin A, Streptomyces plicatus

    Mithramycin A, Streptomyces plicatus

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    M-1072 18378-89-7 1 mg
    $93.06
    5 mg
    $196.46
  18. N-Oxalyl-D-alanine

    N-Oxalyl-D-alanine

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    O-1102 10 mg
    $60.82
    50 mg
    $172.86
  19. NSC-23766

    NSC-23766

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    N-1217 733767-34-5 1 mg
    $69.36
  20. SU 6656

    SU 6656

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2096 330161-87-0 5 mg
    $144.06
    25 mg
    $506.87
  21. SU6668

    SU6668

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2120 210644-62-5 5 mg
    $144.06
    25 mg
    $506.87
  22. Sulochrin, Aspergillus terreus

    Sulochrin, Aspergillus terreus

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2060 519-57-3 1 mg
    $197.41
    5 mg
    $624.25
  23. Suramin hexasodium salt | CAS 129-46-4 | anti-tumor | anti-angiogensis |P2x and P2y Purinergic receptor antagonist. Also shown to be an anti-parasitic and anti-tumor agent. Inhibits angiogenesis. Offered in catalog & bulk quantities by A.G. Scientific.

    Suramin. Hexasodium Salt

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-1012 129-46-4 1 g
    $640.25
  24. Temsirolimus

    Temsirolimus

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    T-2453 162635-04-3 5 mg
    $282.78
    25 mg
    $848.33
  25. Thiolutin

    Thiolutin

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    T-1226 87-11-6 1 mg
    $64.03
    5 mg
    $250.77
  26. Tie-2 Inhibitor 13

    Tie-2 Inhibitor 13

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    T-1182 857250-95-4 Inquire
    $0.00
  27. Tranilast

    Tranilast

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    T-1048 53902-12-8 10 mg
    $51.22
    50 mg
    $202.75
  28. Withaferin A, WFA

    Withaferin A, WFA

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    W-1042 5119-48-2 1 mg
    $84.30
    5 mg
    $266.77
    10 mg
    $576.23